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Source: Molecular and Cellular Biochemistry
Infectious Disease: Hepatitis B
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Total 3 results found since Jan 2013.
Hepatocyte steatosis inhibits hepatitis B virus secretion via induction of endoplasmic reticulum stress
Mol Cell Biochem. 2021 May 13. doi: 10.1007/s11010-021-04143-z. Online ahead of print.ABSTRACTThe effects of hepatocyte steatosis on hepatitis B virus (HBV) DNA replication and HBV-related antigen secretion are incompletely understood. The aims of this study are to explore the effects and mechanism of hepatocyte steatosis on HBV replication and secretion. Stearic acid (SA) and oleic acid (OA) were used to induce HepG2.2.15 cell steatosis in this study. The expressions of glucose-regulated protein 78 (GRP78), phosphorylation of protein kinase R-like endoplasmic reticulum (ER) kinase (p-PERK), and eukaryotic translation init...
Source: Molecular and Cellular Biochemistry - May 13, 2021 Category: Biochemistry Authors: Qichuang Liu Maoyuan Mu Huan Chen Guoyuan Zhang Yanqing Yang Jun Chu Ying Li Fangwan Yang Shide Lin Source Type: research
