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Phosphorylation of Dab2 is involved in inhibited VEGF-VEGFR-2 signaling induced by downregulation of Syndecan-1 in glomerular endothelial cell.
In conclusion, we speculated that, phosphorylation of Dab2 is involved in preventing activation of VEGF-VEGFR-2 signaling in GEnC transfected with Syndecan-1 siRNA. This provide a new target for the therapy of GEnC injury and kidney disease. This article is protected by copyright. All rights reserved. PMID: 31868265 [PubMed - as supplied by publisher]
Source: Cell Biology International - December 22, 2019 Category: Cytology Authors: Jing Z, Jia-Jun W, Wei-Jie Y Tags: Cell Biol Int Source Type: research