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LIPUS suppressed LPS ‐induced IL‐1α through the inhibition of NF‐κB nuclear translocation via AT1‐PLCβ pathway in MC3T3‐E1
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - January 6, 2017 Category: Cytology Authors: Mayu Nagao, Natsuko Tanabe, Soichiro Manaka, Masako Naito, Kumiko Nakai, Tadahiro Takayama, Takayuki Kawato, Go Torigoe, Jumpei Sekino, Naoya Tsukune, Masao Maeno, Naoto Suzuki, Shuichi Sato Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Angiotensin II Activation of TRPC6 Channels in Rat Podocytes Requires Generation of Reactive Oxygen Species
Angiotensin II (AII) plays a major role in the progression of chronic kidney diseases. Podocytes are essential components of the ultrafiltration apparatus, and are targets for AII signaling. AII has been shown to increase generation of reactive oxygen species (ROS) in podocytes. Canonical transient receptor potential‐6 (TRPC6) channels stimulate Ca2+ influx in podocytes, and have been implicated in glomerular disease. We observed that AII increased cationic currents in rat podocytes in an isolated glomerulus preparation in which podocytes are still attached to the underlying capillary. This effect was completely blocked ...
Source: Journal of Cellular Physiology - December 17, 2013 Category: Cytology Authors: Marc Anderson, Hila Roshanravan, Justin Khine, Stuart E. Dryer Tags: Original Research Article Source Type: research

Angiotensin II activation of canonical transient receptor potential‐6 (TRPC6) channels in rat podocytes requires generation of reactive oxygen species
Abstract Angiotensin II (AII) plays a major role in the progression of chronic kidney diseases. Podocytes are essential components of the ultrafiltration apparatus, and are targets for AII signaling. AII has been shown to increase generation of reactive oxygen species (ROS) in podocytes. Canonical transient receptor potential‐6 (TRPC6) channels stimulate Ca2+ influx in podocytes, and have been implicated in glomerular disease. We observed that AII increased cationic currents in rat podocytes in an isolated glomerulus preparation in which podocytes are still attached to the underlying capillary. This effect was completely...
Source: Journal of Cellular Physiology - September 3, 2013 Category: Cytology Authors: Marc Anderson, Hila Roshanravan, Justin Khine, Stuart E. Dryer Tags: Original Research Article Source Type: research