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Source: British Journal of Pharmacology
Condition: Alcoholism
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Total 2 results found since Jan 2013.
Quercetin and allopurinol reduce liver thioredoxin‐interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
Conclusions and ImplicationsInhibition of hepatic TXNIP by quercetin and allopurinol contributes to the reduction in liver inflammation and lipid accumulation under hyperglycaemic conditions. The targeting of hepatic TXNIP by quercetin and allopurinol may have therapeutic implications for prevention of type 1 diabetes‐associated NAFLD.
Source: British Journal of Pharmacology - June 21, 2013 Category: Drugs & Pharmacology Authors: Wei Wang, Chuang Wang, Xiao‐Qin Ding, Ying Pan, Ting‐Ting Gu, Ming‐Xing Wang, Yang‐Liu Liu, Fu‐Meng Wang, Shui‐Juan Wang, Ling‐Dong Kong Tags: Research Paper Source Type: research
Sulforaphane protects against ethanol‐induced oxidative stress and apoptosis in neural crest cells by the induction of Nrf2‐mediated antioxidant response
Conclusions and implicationsThese results demonstrated that Nrf2‐mediated antioxidant response plays an important role in the susceptibility of NCCs to ethanol‐induced oxidative stress and apoptosis and that the protection of SFN against ethanol‐induced oxidative stress and apoptosis in NCCs is mediated by the induction of Nrf2 signaling.
Source: British Journal of Pharmacology - February 20, 2013 Category: Drugs & Pharmacology Authors: X Chen, J Liu, S‐Y Chen Tags: Research Paper Source Type: research
