• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Sirtuin‐6 deficiency exacerbates diabetes‐induced impairment of wound healing
Abstract Delayed wound healing is one of the major complications in diabetes and is characterized by chronic proinflammatory response, and abnormalities in angiogenesis and collagen deposition. Sirtuin family proteins regulate numerous pathophysiological processes, including those involved in promotion of longevity, DNA repair, glycolysis and inflammation. However, the role of sirtuin 6 (SIRT6), a NAD+‐dependent nuclear deacetylase, in wound healing specifically under diabetic condition remains unclear. To analyse the role of SIRT6 in cutaneous wound healing, paired 6‐mm stented wound was created in diabetic db/db mice...
Source: Experimental Dermatology - August 18, 2015 Category: Dermatology Authors: Rajarajan A. Thandavarayan, Venkata Naga Srikanth Garikipati, Darukeshwara Joladarashi, Sahana Suresh Babu, Prince Jeyabal, Suresh K. Verma, Alexander R. Mackie, Mohsin Khan, Somasundaram Arumugam, Kenichi Watanabe, Raj Kishore, Prasanna Krishnamurthy Tags: Original Article Source Type: research

Sirtuin‐6 deficiency exacerbates diabetes induced impairment of wound healing
This article is protected by copyright. All rights reserved.
Source: Experimental Dermatology - May 23, 2015 Category: Dermatology Authors: Rajarajan A Thandavarayan, Venkata Naga Srikanth Garikipati, Joladarashi Darukeshwara, Sahana Suresh Babu, Prince Jeyabal, Suresh K Verma, Alexander R Mackie, Mohsin Khan, Somasundaram Arumugam, Kenichi Watanabe, Raj Kishore, Prasanna Krishnamurthy Tags: Regular Article Source Type: research