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Source: Molecular Cancer
Education: Students
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MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1
Conclusion:
Our study’s results are consistent with miR-497 being a candidate tumor suppressor in neuroblastoma, through the direct targeting of WEE1. These findings re-enforce the proposal of WEE1 as a therapeutic target in neuroblastoma.
Source: Molecular Cancer - March 26, 2013 Category: Cancer & Oncology Authors: Laura CreeveyJacqueline RyanHarry HarveyIsabella BrayMaria MeehanAdnan KhanRaymond Stallings Source Type: research
