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Tumor Necrosis Factor- α Induces Claudin-3 Upregulation in Kidney Tubular Epithelial Cells through NFκB and CREB1.
Tumor Necrosis Factor-α Induces Claudin-3 Upregulation in Kidney Tubular Epithelial Cells through NFκB and CREB1. Am J Physiol Cell Physiol. 2021 Jan 13;: Authors: Anwer S, Branchard E, Dan Q, Dan A, Szaszi K Abstract Claudins are essential for tight junction formation and paracellular transport, and affect key cellular events including proliferation and migration. The properties of tight junctions are dynamically modulated by a variety of inputs. We previously showed that the inflammatory cytokine Tumor Necrosis Factor-α (TNFα), a major pathogenic factor in kidney disease, alters epithelial perme...
Source: Am J Physiol Cell Ph... - January 13, 2021 Category: Cytology Authors: Anwer S, Branchard E, Dan Q, Dan A, Szaszi K Tags: Am J Physiol Cell Physiol Source Type: research