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Condition: Cholesterol
Drug: Nicotine
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Total 2 results found since Jan 2013.
Attenuated cholesterol metabolism pathway suppresses regulatory T cell development in prenatal nicotine exposed female mice.
In conclusion, this study showed that PNE could suppress Tregs development in female mice by up-regulating ABCG1-dependent cholesterol efflux, and suggested that PNE-induced thymic Tregs recession of offspring at early life was the developmental origin mechanism of immune dysfunction in later life.
PMID: 31629012 [PubMed - as supplied by publisher]
Source: Toxicology - October 15, 2019 Category: Toxicology Authors: Wen X, Zhao WH, Chen LZ, Qu W, Liu HX, Yan HY, Hou LF, Ping J Tags: Toxicology Source Type: research
Pravastatin activates activator protein 2 alpha to argument the angiotensin II-induced abdominal aortic aneurysms.
In conclusion, pravastatin promotes AAA formation through AMPKα2-dependent AP-2α activations.
PMID: 28179583 [PubMed - as supplied by publisher]
Source: Oncotarget - February 11, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research
