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Source: J Cell Mol Med
Drug: Eloxatin
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Total 2 results found since Jan 2013.
siRNA-induced CD44 knockdown suppresses the proliferation and invasion of colorectal cancer stem cells through inhibiting epithelial-mesenchymal transition
J Cell Mol Med. 2022 Mar 1. doi: 10.1111/jcmm.17221. Online ahead of print.ABSTRACTCD44 has shown prognostic values and promising therapeutic potential in multiple human cancers; however, the effects of CD44 silencing on biological behaviors of cancer stem cells (CSCs) have not been fully understood in colorectal cancer. To examine the contribution of siRNA-induced knockdown of CD44 to the biological features of colorectal CSCs, colorectal CSCs HCT116-CSCs were generated, and CD44 was knocked down in HCT116-CSCs using siRNA. The proliferation, migration and invasion of HCT116-CSCs were measured, and apoptosis and cell-cycl...
Source: J Cell Mol Med - March 1, 2022 Category: Molecular Biology Authors: Weiyan Zou Yi Zhang Guangfu Bai Jialu Zhuang Lin Wei Zishu Wang Meiqun Sun Junbin Wang Source Type: research
