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Therapeutic potential of topical administration of siRNAs against HIF-1 α for corneal neovascularization
In conclusion, the topical application of siRNA towards HIF-1α seems to be an effective and reliable method to stop neovascularization.PMID:35367249 | DOI:10.1016/j.exer.2022.109036
Source: Cell Research - April 3, 2022 Category: Cytology Authors: Assumpta Peral Jes ús Mateo Carmen O Dom ínguez-Godínez Gonzalo Carracedo Jose Antonio G ómez Almudena Crooke Jes ús Pintor Source Type: research

Nanog/NFATc1/Osterix signaling pathway-mediated promotion of bone formation at the tendon-bone interface after ACL reconstruction with De-BMSCs transplantation
CONCLUSIONS: De-BMSCs transplantation could promote bone formation at the tendon-bone interface after ACLR and improve the biomechanical strength of the reconstruction. The Nanog/NFATc1/Osterix signaling pathway mediated the enhanced osteogenic differentiation efficiency of De-BMSCs.PMID:34775995 | DOI:10.1186/s13287-021-02643-9
Source: Cell Research - November 15, 2021 Category: Cytology Authors: Kai Tie Jinghang Cai Jun Qin Hao Xiao Yangfan Shangguan Hui Wang Liaobin Chen Source Type: research