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In vitro evaluation of anti HSV ‐1 siRNAs and in vivo evaluation of electroporation to transfect siRNAs on murine cornea
ConclusionsThese results demonstrate that siRNA directed against HSV‐1 DNA polymerase efficiently inhibits HSV‐1 replication, suggesting that siRNA based antiviral strategy may be a potential therapeutic alternative to treat HSK. Besides, intracorneal penetration may be facilitated by electroporation.
Source: Acta Ophthalmologica - September 13, 2016 Category: Opthalmology Authors: A. Rousseau, V. Escriou, P. Roy, N. Poccardi, J. Takissian, P. Bigey, M. Labetoulle Tags: Abstracts from the 2016 European Association for Vision and Eye Research Conference Source Type: research