Adhesion of silicone oil and emulsification: an in  vitro assessment using a microfluidic device and ‘Eye‐on‐a‐Chip’
ConclusionA new mechanism of emulsification of SiO is proposed: SiO adheres to ocular tissue to form emulsified droplets. The presence of HMW, which increases the extensional viscosity, may resist the break ‐up of SiO from the substrate to form emulsified droplets. When tested in a physiologically representative platform, the use of HMW in SiO generally reduces the number of droplets formedin  vitro. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 28, 2018 Category: Opthalmology Authors: Yongjie Lu, Yau Kei Chan, Long Hei Lau, Youchuang Chao, Kendrick Co Shih, Shiu Ming Lai, David Wong, Ho Cheung Shum Tags: Original Article Source Type: research

Exposure to antazoline ‐naphazoline eye drops during pregnancy and the risk of congenital malformations: a Danish nationwide cohort study
AbstractPurposeTo investigate whether exposure to antazoline ‐naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans.MethodsAll women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at least one prescription of antazoline ‐naphazoline eye drops during the first 84 days of pregnancy were identified. Logistic regression was used to estimate the odds ratios of malformations among exposed offspring compared to non‐exposed offspring.ResultsWe identified 977  706 births between...
Source: Acta Ophthalmologica - November 26, 2018 Category: Opthalmology Authors: Vilde Thomseth, Vanja Cejvanovic, Espen Jimenez ‐Solem, Henrik E. Poulsen, Tor Paaske Utheim, Jon T. Andersen Tags: Original Article Source Type: research

Issue Information
Acta Ophthalmologica, Volume 96, Issue 7, Page 655-658, November 2018. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 25, 2018 Category: Opthalmology Tags: Issue Information Source Type: research

This issue of Acta
Acta Ophthalmologica, Volume 96, Issue 7, Page 659-660, November 2018. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 25, 2018 Category: Opthalmology Authors: Einar Stef ánsson Tags: This issue of Acta Source Type: research

Efficacy and safety of vitrectomy for congenital cataract surgery: a systematic review and meta ‐analysis based on randomized and controlled trials
ConclusionVitrectomy helps lower the PCO risk and reoperation risk after congenital cataract surgery, and also, vitrectomy helps patients gain a better BCVA and achieve a better low ‐contrast sensitivity, with no trade‐off on IOP control, IOL deposit, synechias, uveitis and secondary glaucoma. We recommend performing vitrectomy during congenital cataract surgery. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 22, 2018 Category: Opthalmology Authors: Kai Cao, Jinda Wang, Jingshang Zhang, Mayinuer Yusufu, Shanshan Jin, Simeng Hou, Guyu Zhu, Bingsong Wang, Ying Xiong, Jing Li, Xiaoxia Li, Lijing Chai, Hailong He, Xiu H. Wan Tags: Original Article Source Type: research

Comparison of MultiColor fundus imaging and colour fundus photography in the evaluation of epiretinal membrane
ConclusionThe ERM area is more clearly detectable and widely demarcated in MC than in CFP images. MultiColor imaging (MC) may be more sensitive and accurate for early detection of ERM and ERM area measurement. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 22, 2018 Category: Opthalmology Authors: Ji Hun Song, Ka Young Moon, Seran Jang, YeoRae Moon Tags: Original Article Source Type: research

Hair cortisol concentration in patients with active central serous chorioretinopathy is elevated – a pilot study
ConclusionPatients with active CSC have increased HCC, supporting the fact that cortisol is a major player in CSC pathogenesis. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 22, 2018 Category: Opthalmology Authors: Janine Lenk, Dirk Sandner, Lena Schindler, Lutz E. Pillunat, Egbert Matth é Tags: Original Article Source Type: research

Retinal oximetry and systemic arterial oxygen levels
AbstractPurposeContinuous peripheral pulse oximetry for monitoring adequacy of oxygenation is probably the most important technological advance for patients ’ monitoring and safety in the last decades. Pulse oximetry has the disadvantage of measuring the peripheral circulation, and the only mean to measure oxygen content of the central circulation is by invasive technology. Determination of blood oxyhaemoglobin saturation in the retinal vessels of the eye can be achieved noninvasively through spectrophotometric retinal oximetry which provides access to the central nervous system circulation. The aim of the thesis was...
Source: Acta Ophthalmologica - November 20, 2018 Category: Opthalmology Authors: Thorunn Scheving Eliasdottir Tags: Thesis Source Type: research

Risk factors for high myopia: a 22 ‐year follow‐up study from childhood to adulthood
AbstractPurposeTo determine the effect of the definition of high myopia on its prevalence and risk factors for high myopia.MethodsA total of 240 myopic schoolchildren (119 boys and 121 girls) at the mean age of 10.9  years (range 8.8–12.8 years) were recruited to a randomized clinical trial of myopia treatment among children from 3rd‐ and 5th grades of school referred for an eye examination due to poor distant vision and having no previous spectacles. Clinical follow‐ups, including refraction with cyclo plegia, were conducted annually at 3 years [third follow‐up here = clinical follow...
Source: Acta Ophthalmologica - November 20, 2018 Category: Opthalmology Authors: Olavi P ärssinen, Markku Kauppinen Tags: Original Article Source Type: research

Automatic detection of diabetic retinopathy and its progression in sequential fundus images of patients with diabetes
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 18, 2018 Category: Opthalmology Authors: Alexander Dietzel, Carolin Schanner, Aura Falck, Nina Hautala Tags: Letter to the Editor Source Type: research

Efficacy and safety of treatment of hyposecretory dry eye with platelet ‐rich plasma
AbstractObjectiveTo evaluate and compare the symptomatology and clinical findings in hyposecretory dry eye of the treatment with platelet ‐rich plasma (PRP) and artificial tears of sodium hyaluronate (SH).MethodsBlind single ‐centre prospective comparative randomized study including 83 patients with hyposecretory dry eye and mean age of 64.0 years. Two groups were differentiated depending on the treatment applied: 44 patients treated with PRP (PRP group), and 39 patients treated with artificial tears of SH (SH group) . Changes in Schimer test, tear osmolarity, corneal and conjunctival staining, tear film break‐u...
Source: Acta Ophthalmologica - November 18, 2018 Category: Opthalmology Authors: V íctor García‐Conca, Marta Abad‐Collado, Jose R Hueso‐Abancens, Encarna Mengual‐Verdú, David P Piñero, Fernando Aguirre‐Balsalobre, Julio C Molina Tags: Original Article Source Type: research

The relationship between retinal thickness and neurodegeneration in early diabetic patients
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 18, 2018 Category: Opthalmology Authors: Muhammed Şahin, Alparslan Şahin, Fatih Mehmet Türkcü Tags: Letter to the Editor Source Type: research

A nationwide population ‐based study of social demographic factors, associated diseases and mortality of keratoconus patients in Denmark from 1977 to 2015
ConclusionDanish keratoconus patients differ from controls on several sociodemographic factors and have higher risk of allergic rhinitis, asthma, atopic dermatitis and depression. They do not have excess mortality compared to controls. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 13, 2018 Category: Opthalmology Authors: Sashia Bak ‐Nielsen, Cecilia H. Ramlau‐Hansen, Anders Ivarsen, Oleguer Plana‐Ripoll, Jesper Hjortdal Tags: Original Article Source Type: research

IgG4 ‐related disease in patients with idiopathic orbital inflammation syndrome: data from the French SIOI prospective cohort
ConclusionsMore than one ‐third of patients with biopsy‐proven IOIS satisfied criteria for IgG4‐RD, but only a few had a definite type. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 12, 2018 Category: Opthalmology Authors: S ébastien Abad, Antoine Martin, Francoise Héran, Nahla Cucherousset, Frédéric Mouriaux, Emmanuel Héron, Neila Sédira, Mathieu Zmuda, Matthieu Groh, Aïcha Abbas, David Saadoun, Pierre Aucouturier, Eric Vicaut, Robin Dhote, for the Fr Tags: Original Article Source Type: research

Biomechanical efficacy of contact lens ‐assisted collagen cross‐linking in porcine eyes
ConclusionsThe biomechanical effect of CACXL in porcine corneas is about one ‐third less than after standard CXL. The efficacy of CACXL might be improved by reducing or omitting the riboflavin film on the contact lens. Further risk assessment studies are necessary. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 12, 2018 Category: Opthalmology Authors: Gregor Wollensak, Eberhard Sp örl, Hermann Herbst Tags: Original Article Source Type: research

Efficacy of bevacizumab for posttraumatic choroidal neovascularization
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 9, 2018 Category: Opthalmology Authors: Kwangsic Joo, Taewoong Um, Sang Jun Park, Joon Hee Cho, Jeeyun Ahn, Jee Taek Kim, Joo Yong Lee, Kyu Hyung Park, Se Joon Woo Tags: Letter to the Editor Source Type: research

Associations of cytokine concentrations in aqueous humour with retinal vascular abnormalities and exudation in Coats ’ disease
AbstractPurposeTo investigate the associations of cytokine concentrations in aqueous humour with the severity of retinal vascular abnormalities, exudation and fibrosis in patients with Coats ’ disease.MethodsAqueous humour samples were collected in 23 paediatric patients (23 eyes) with Coats ’ disease and six age‐matched control patients (six eyes) with congenital cataract in this cross‐sectional, case–control study. Through Cytometric Bead Array technology, six angiogenic, inflammatory and fibrotic cytokines were measured for their concentrations in aqueous humour. Ophthalmolog ic characteristics inc...
Source: Acta Ophthalmologica - November 9, 2018 Category: Opthalmology Authors: Juan Zhang, Chen Jiang, Lu Ruan, Xin Huang Tags: Original Article Source Type: research

The tick sign – a new and simple test to diagnose keratoconus at the slit lamp
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 8, 2018 Category: Opthalmology Authors: Marcus ‐Matthias Gellrich Tags: Letter to the Editor Source Type: research

Automatic computer ‐aided analysis of optic disc pallor in fundus photographs
ConclusionsWe developed an automated CAD system that successfully detected optic disc pallor in fundus photographs. The proposed algorithm can assist the clinical judgement of ophthalmologists for detecting optic disc pallor in fundus photographs. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 8, 2018 Category: Opthalmology Authors: Hee Kyung Yang, Ji Eun Oh, Sang Beom Han, Kwang Gi Kim, Jeong ‐Min Hwang Tags: Original Article Source Type: research

Maternal smoking during pregnancy and the risk of strabismus in offspring: a meta ‐analysis
AbstractThe effect of maternal smoking during pregnancy on strabismus in offspring remains unclear. We conducted a meta ‐analysis to summarize epidemiological evidences on the association between maternal smoking during pregnancy and the risk of offspring strabismus. Eligible studies were searched from the PubMed, Ovid, Embase and CNKI databases up to May 2018. The qualities of included articles were assessed with the Newcastle–Ottawa Scale and the assessment scale recommended by the Agency for Healthcare Research and Quality. Odds ratios (ORs) corresponding with its 95% confidence intervals (CIs) were pooled to es...
Source: Acta Ophthalmologica - November 6, 2018 Category: Opthalmology Authors: Yudi Yang, Chao Wang, Yong Gan, Heng Jiang, Wenning Fu, Shiyi Cao, Zuxun Lu Tags: Review Article Source Type: research

Prevalence of anterior polar cataracts in children and risk factors for amblyopia
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 3, 2018 Category: Opthalmology Authors: Asrin Rasul, Line Kessel Source Type: research

Toy gun eye injuries – eye protection needed Helsinki ocular trauma study
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 3, 2018 Category: Opthalmology Authors: Anna ‐Kaisa Haavisto, Ahmad Sahraravand, Päivi Puska, Tiina Leivo Source Type: research

New compound heterozygous USH2A mutations in Usher syndrome
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 3, 2018 Category: Opthalmology Authors: Longhao Kuang, Qingshan Chen, Run Gan, Xiaohe Yan Source Type: research

Efficacy of lateral eyelid ‐block excision with canthoplasty and full‐thickness skin grafting in lower eyelid cicatricial ectropion
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - November 2, 2018 Category: Opthalmology Authors: Ilse Mol, Dion Paridaens Source Type: research

Genetic influence on contrast sensitivity in young adults
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 31, 2018 Category: Opthalmology Authors: Koen V. Haak Source Type: research

Maladaptive personality traits, psychological morbidity and coping strategies in chronic central serous chorioretinopathy
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 31, 2018 Category: Opthalmology Authors: Femke M. Haalen, Elon H.C. Dijk, Cornelie D. Andela, Greet Dijkman, Nienke R. Biermasz, Alberto M. Pereira, Camiel J.F. Boon Source Type: research

Persisting diplopia after periocular injection of parallel imported Kenalog ® (triamcinolone acetonide)
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 28, 2018 Category: Opthalmology Authors: K åre Clemmensen, Mette Slot Nielsen, Susanne Krag Source Type: research

Macular perfusion velocities in the ocular ischaemic syndrome
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 28, 2018 Category: Opthalmology Authors: Oliver Niels Klefter, Peter Kristian Kofoed, Inger Christine Munch, Michael Larsen Source Type: research

Are the real ‐life outcomes of using aflibercept in diabetic macular oedema comparable to the landmark studies?
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 28, 2018 Category: Opthalmology Authors: Aisling K. Higham, Muhammad I. Tahir, Kavita Gala, Georgios Verroiopoulos Source Type: research

Reducing avoidable visual impairment in elderly home healthcare patients by basic ophthalmologic screening
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 28, 2018 Category: Opthalmology Authors: Ruth Nispen, Hilde Aa, Frank Timmermans, Nikki Meijer, Nicole Koster, Jos de Blok, Jan Keunen, Ger Rens Source Type: research

Bevacizumab in age ‐related macular degeneration: a randomized controlled trial on the effect of on‐demand therapy every 4 or 8 weeks
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 28, 2018 Category: Opthalmology Authors: Sankha Amarakoon, Jos é P. Martinez‐Ciriano, L. Ingeborgh Born, Seerp Baarsma, Tom Missotten Source Type: research

Effects of bifocals on visual acuity in children with Down syndrome: a randomized controlled trial
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 27, 2018 Category: Opthalmology Authors: Christine Weger, Nienke Boonstra, Jeroen Goossens Source Type: research

Metabolic syndrome and some of its components in relation to risk of cataract extraction. A prospective cohort study of men
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 24, 2018 Category: Opthalmology Authors: Birgitta Ejdervik Lindblad, Niclas H åkansson, Alicja Wolk Source Type: research

Semi ‐automated kinetic perimetry: Comparison of the Octopus 900 and Humphrey visual field analyzer 3 versus Goldmann perimetry
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 22, 2018 Category: Opthalmology Authors: Claudia Bevers, Gauthier Blanckaert, Karel Van Keer, Jean ‐François Fils, Evelien Vandewalle, Ingeborg Stalmans Source Type: research

The cost ‐effectiveness of alternative vision screening models among preschool children in rural China
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 22, 2018 Category: Opthalmology Authors: Lei Wang, Nathan Congdon, Ruth E. Hogg, Siqi Zhang, Mengjie Li, Yaojiang Shi, Ling Jin, Fei He, Huan Wang, Matthew Boswell, Mony Iyer Source Type: research

Physical activity and eye diseases. The Beijing Eye Study
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 19, 2018 Category: Opthalmology Authors: Ya Xing Wang, Wen Bin Wei, Liang Xu, Jost B. Jonas Source Type: research

Sensitivity and specificity of school nurse screening for hypermetropia and convergence insufficiency exophoria in primary schoolchildren in Denmark
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 19, 2018 Category: Opthalmology Authors: Ivan Nisted, Marianne Ledet Maagaard, Lotte Welinder Source Type: research

Macular versus nerve fibre layer versus optic nerve head imaging for diagnosing glaucoma at different stages of the disease: Multicenter Italian Glaucoma Imaging Study
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 19, 2018 Category: Opthalmology Authors: Manuele Michelessi, Ivano Riva, Enrico Martini, Michele Figus, Paolo Frezzotti, Luca Agnifili, Gianluca Manni, Luciano Quaranta, Stefano Miglior, Chiara Posarelli, Stefano Fazio, Francesco Oddone Source Type: research

Unexpected ABCC6 mRNA splicing in a Chinese family with pseudoxanthoma elasticum
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 17, 2018 Category: Opthalmology Authors: Qiao Sun, Weijun Wang, Lifang Wu, Lu Cheng, Xuemei Tong, Xun Xu Source Type: research

The great imitator on the rise: ocular and optic nerve manifestations in patients with newly diagnosed syphilis
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 17, 2018 Category: Opthalmology Authors: Ainat Klein, Naomi Fischer, Michaella Goldstein, Shiri Shulman, Zohar Habot ‐Wilner Source Type: research

Predicting undetected glaucoma according to age and IOP: a prediction model developed from a primarily European ‐derived population
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 16, 2018 Category: Opthalmology Authors: Sigridur E. Oskarsdottir, Anders Heijl, Boel Bengtsson Source Type: research

Comparison between 90 ‐degree and 360‐degree selective laser trabeculoplasty (SLT): A 2‐year follow‐up
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Kozar Tawfique, Pardis Khademi, Laurence Qu érat, Joobin Khadamy, Enping Chen Source Type: research

Dexamethasone for unresponsive diabetic macular oedema: optical coherence tomography biomarkers
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Vincenza Bonfiglio, Michele Reibaldi, Alessandra Pizzo, Andrea Russo, Iacopo Macchi, Giuseppe Faro, Teresio Avitabile, Antonio Longo Source Type: research

Achieving balance in the treatment and monitoring of neovascular age ‐related macular degeneration in the real world: lessons from the Netherlands cohort of the AURA study
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Freekje Asten, Yvonne Jong ‐Hesse, Janneke J. C. Lith‐Verhoeven, Frank D. Verbraak, Johannes G. F. Vromans, Nga‐Chi Lau, Andreas Altemark, Carel B. Hoyng Source Type: research

The value of cycloplegia in optometric refraction of adults in a population study
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Catherine Jan, Nathan Congdon, Weihe Zhou, Brendan Ross, Ningli Wang, Yuanbo Liang Source Type: research

Inconsistent distortion in ultra ‐widefield fundus image
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Danson Vasanthan Muttuvelu, Jens Folke Kiilgaard Source Type: research

Impact of donor tissue diameter on postoperative central endothelial cell density in Descemet Membrane Endothelial Keratoplasty
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Silvia Schrittenlocher, Bj örn Bachmann, Claus Cursiefen Source Type: research

Retinal nerve fibre layer evaluation in multiple sclerosis patients with and without optic neuritis
Acta Ophthalmologica, EarlyView. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Fabiana F. Gon çalves, Luiz F. A. Lucatto, Andre S. Camargo, Alessandra B. Falcão, Luiz Alberto S. Melo, Eric P. Andrade, Tiago de A. Macruz, Denis B. Bichuetti, Enedina M. L. Oliveira, Ivan M. Tavares Source Type: research

Issue Information
Acta Ophthalmologica,Volume 96, Issue 6, Page 533-536, September 2018. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Source Type: research

This issue of Acta Sept 2018
Acta Ophthalmologica,Volume 96, Issue 6, Page 537-538, September 2018. (Source: Acta Ophthalmologica)
Source: Acta Ophthalmologica - October 15, 2018 Category: Opthalmology Authors: Einar Stef ánsson Source Type: research