Filtered By:
Condition: Benign Prostatic Hyperplasia
This page shows you your search results in order of date. This is page number 5.
Order by Relevance | Date
Total 117 results found since Jan 2013.
Silencing of hepsin and inosine 5-monophosphate dehydrogenase 2 by siRNA reduces prostate cancer cells proliferation
This study aimed to determine the transcript level of PCa-related genes, HPN and IMPDH2, in archived tissues. Their functional roles were further determined using an in vitro model of PCa. Total RNA extraction was done from formalin-fixed paraffin-embedded PCa tissues, and benign prostatic hyperplasia (BPH) tissues acted as the control. Quantitative real-time polymerase chain reaction (qPCR) was performed to measure HPN and IMPDH2 expression. The functional assay was performed in a prostate cancer cell line (DU145) on these two genes by silencing their RNA. We discovered a significantly higher expression of IMPDH2 in PCa s...
Source: Malaysian Journal of Pathology - April 29, 2022 Category: Pathology Authors: N A Wahab H D Dardar R Yunus Z M Zainudin N M Mokhtar Source Type: research
