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TXNIP-NLRP3 Binding in Podocyte Inflammasomes Metabolism
In conclusion, our results demonstrate that TXNIP binding to NLRP3 is a key signaling mechanism necessary for hHcys-induced NLRP3 inflammasome formation and activation and subsequent glomerular injury.
Source: Journal of Biological Chemistry - September 25, 2014 Category: Chemistry Authors: Abais, J. M., Xia, M., Li, G., Chen, Y., Conley, S. M., Gehr, T. W. B., Boini, K. M., Li, P.-L. Tags: Molecular Bases of Disease Source Type: research
