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Condition: Thrombosis
Infectious Disease: Parasitic Diseases
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Plasmodium falciparum histidine rich protein HRPII inhibits the antiinflammatory function of antithrombin.
CONCLUSION: We postulate that Pf-derived HRPII and polyphosphate can contribute to the pathogenesis of malaria infection by downregulating the AT-dependent antiinflammatory and anticoagulant pathways.
PMID: 31858717 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - December 18, 2019 Category: Hematology Authors: Dinarvand P, Yang L, Biswas I, Giri H, Rezaie AR Tags: J Thromb Haemost Source Type: research
