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Condition: Translocation
Therapy: Incretin Therapy
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Total 1 results found since Jan 2013.
The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1
ConclusionsThese data demonstrate, for the first time, that mice display a circadian pattern in GLP-1 secretion, which is impaired in Bmal1 knockout mice, and that Bmal1 regulation of Scgn expression plays an essential role in the circadian release of the incretin hormone, GLP-1.
Source: Molecular Metabolism - November 21, 2019 Category: Endocrinology Source Type: research
