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Condition: Psoriasis
Drug: Acitretin
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Total 1 results found since Jan 2013.
Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling
Publication date: Available online 8 May 2017 Source:Saudi Pharmaceutical Journal Author(s): Xuan Qin, Chunna Chen, Yuan Zhang, Li Zhang, Yijie Mei, Xinchun Long, Rui Tan, Ledong Sun Acitretin has been a valuable option for the treatment of psoriasis, however, the molecular events of acitretin leading to the normalization of keratinocytes differentiation on psoriasis patients have not been fully explored. To investigate whether there were certain relationship between keratinocytes proliferation and JAK/STAT signaling pathways in psoriasis, and how acitretin modulated the signaling pathways. HaCaT cells, an in vitro immort...
Source: Saudi Pharmaceutical Journal - May 9, 2017 Category: Drugs & Pharmacology Source Type: research
