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Total 31 results found since Jan 2013.

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy.
CONCLUSIONS: The enrichment results and functional example imply that cellular models of chemotherapeutic toxicity may capture components of the underlying polygenic architecture of related traits in patients. PMID: 23204130 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - November 30, 2012 Category: Cancer & Oncology Authors: Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman L, Nakamura Y, Ratain MJ, Kroetz D, Cox NJ, Dolan ME Tags: Clin Cancer Res Source Type: research