• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Knockdown of lncRNA < em > HOXD-AS2 < /em > Improves the Prognosis of Glioma Patients by Inhibiting the Proliferation and Migration of Glioma Cells
CONCLUSION: HOXD-AS2 is an oncogenic lncRNA associated with the poor prognosis of glioma. Knockdown of HOXD-AS2 may reduce the growth of glioma, which may provide a new avenue for treatment.PMID:36408341 | PMC:PMC9668444 | DOI:10.1155/2022/9337647
Source: Evidence-based Complementary and Alternative Medicine - November 21, 2022 Category: Complementary Medicine Authors: Feng Chen Ru-Ru Zhao Qian Li Zhen-Hua Chen Chun Luo Source Type: research

Intracellular Progesterone Receptor and cSrc Protein Working Together to Regulate the Activity of Proteins Involved in Migration and Invasion of Human Glioblastoma Cells
Glioblastomas are the most common and aggressive primary brain tumors in adults, and patients with glioblastoma have a median survival of 15 months. Some alternative therapies, such as Src family kinase inhibitors, have failed presumably because other signaling pathways compensate for their effects. In the last ten years, it has been proven that sex hormones such as progesterone (P4) can induce growth, migration, and invasion of glioblastoma cells through its intracellular progesterone receptor (PR), which is mostly known for its role as a transcription factor, but it can also induce non-genomic actions. These non-classic ...
Source: Frontiers in Endocrinology - March 26, 2021 Category: Endocrinology Source Type: research