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Increased Expression of FGF19 Contributes to Tumor Progression and Cell Motility of Human Thyroid Cancer
Conclusion Our data revealed that the increased expression of FGF19 might be involved in the malignant behaviors of thyroid cancer, highlighting its potential as a molecular marker for early diagnosis and as a possible target for therapeutic intervention of this disease.
Source: Otolaryngology - Head and Neck Surgery - January 6, 2016 Category: ENT & OMF Authors: Zhang, X., Wang, Z., Tian, L., Xie, J., Zou, G., Jiang, F. Tags: Endocrine Surgery Source Type: research

Plasminogen activator inhibitor‐1 as regulator of tumor‐initiating cell properties in head and neck cancers
ConclusionThe inhibition of PAI‐1 by PAI‐039 or siRNA could suppress head and neck cancer‐TICs within head and neck cancer cell lines through the downregulation of Sox2. © 2015 Wiley Periodicals, Inc. Head Neck, 2015
Source: Head and Neck - July 16, 2015 Category: ENT & OMF Authors: Yueh‐Chun Lee, Cheng‐Chia Yu, Chih Lan, Che‐Hsin Lee, Hsueh‐Te Lee, Yu‐Liang Kuo, Po‐Hui Wang, Wen‐Wei Chang Tags: Original Article Source Type: research

Plasminogen activator inhibitor‐1 regulates tumor initiating cell properties in head and neck cancers
Conclusion The inhibition of PAI‐1 by PAI‐039 or siRNA could suppress HNC‐TICs within HNC cell lines through the down‐regulation of Sox2. This article is protected by copyright. All rights reserved.
Source: Head and Neck - May 1, 2015 Category: ENT & OMF Authors: Yueh‐Chun Lee, Cheng‐Chia Yu, Chih Lan, Che‐Hsin Lee, Hsueh‐Te Lee, Yu‐Liang Kuo, Po‐Hui Wang, Wen‐Wei Chang Tags: Original Article Source Type: research