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Specialty: ENT & OMF
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Total 59 results found since Jan 2013.
Effect of Neurokinin-1 Receptor Knockdown on the Expression of RANTES in Allergic Rhinitis
Am J Rhinol Allergy. 2023 Jul 31:19458924231191012. doi: 10.1177/19458924231191012. Online ahead of print.ABSTRACTBACKGROUND: Neurokinin-1 receptor (NK-1R) and normal T cell expressed and secreted (RANTES) have been shown to play important roles in allergic rhinitis (AR). However, whether the regulating effect of NK-1R in AR is achieved via RANTES remains unknown.METHODS: In the present study, Sprague-Dawley rats were sensitized and challenged with ovalbumin to make AR models. During the challenge period, the rats were treated intranasally with NK-1R-specific small interfering RNA (siRNA) for NKR group, negative siRNA for ...
Source: American Journal of Rhinology and Allergy - August 1, 2023 Category: ENT & OMF Authors: Hong Wang Jing Wu Ruxin Zhang Source Type: research
MiR-214 Expression Is Elevated in Chronic Rhinosinusitis Mucosa and Regulates Lipopolysaccharide-Mediated Responses in Undifferentiated Human Nasal Epithelial Cell Culture
CONCLUSION: Taken together, miR-214 regulates LPS-mediated inflammation and MUC5AC expression via targeting SIRT1, and STAT3/GDF15 may involve in the regulation of miR-214 inhibitor on inflammation and MUC5AC expression.PMID:36797977 | DOI:10.1177/19458924231152683
Source: American Journal of Rhinology and Allergy - February 17, 2023 Category: ENT & OMF Authors: Zhou Wang Dong Lin Yuxiang Zhao Hui Liu Ting Yang An Li Source Type: research
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate
CONCLUSIONS: BMP4 enhances cell migration and promotes cell EMT through Smad1 signaling pathway. Abnormal BMP4 mediates migration and EMT through other relevant signaling pathways resulting in NSCL/P. The study provides new insight into the mechanisms of NSCL/P associated with BMP4.n.PMID:35702016 | DOI:10.1177/10556656221105762
Source: The Cleft Palate-Craniofacial Journal - June 15, 2022 Category: ENT & OMF Authors: Jia-Wei Hong Yue Yu Lu-Shan Wang Zheng Li Rui Zhang Qi Wang Zhen Ding Jin-Peng Zhang Mei-Rong Zhang Li-Chun Xu Source Type: research
Changes in mucin production in human airway epithelial cells after exposure to e-cigarette vapor with or without nicotine.
Conclusion: E-cigarettes vapor with and with nicotine is significantly increased MUC5AC expression in human airway epithelial cells.
PMID: 33355840 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Otorhinolaryngology - December 29, 2020 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
Assessment of cervical lymph node metastasis based on total RNA from saliva and tumor tissue in patients with oral squamous cell carcinoma: An observational study
Conclusion: Saliva and tumor tissue RNA can be a good marker for pretreatment assessment of lymph node metastasis in patients with OSCC. Although the diagnostic accuracy which range from 63% to 65%, further characterization and study of specific mRNA, siRNA and miRNA may come out with high diagnostic accuracy.
Source: Journal of Oral and Maxillofacial Pathology - September 8, 2020 Category: ENT & OMF Authors: Kiran B Jadhav Vandana Shah Ghansham Parmar Nirali Chauhan Naveen Shah Nidhi Gupta Source Type: research
