Association between childhood maltreatment and suicidal ideation among Chinese patients with chronic schizophrenia: the mediating role of insomnia - Hao Y, Peng P, Wang Q, Zhou Y, Chen S, Wu Q, Liu T, Zhang X.
BACKGROUND: Childhood maltreatment is a well-established transdiagnostic risk factor for suicidal ideation; however, previous studies on their association in schizophrenia have produced highly varied results. Moreover, the mechanism linking childhood maltr... (Source: SafetyLit)
Source: SafetyLit - May 6, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Belief updating, childhood maltreatment, and paranoia in schizophrenia-spectrum disorders - Sloan AF, Kittleson AR, Torregrossa LJ, Feola B, Rossi-Goldthorpe R, Corlett PR, Sheffield JM.
BACKGROUND AND HYPOTHESIS: Exposure to childhood maltreatment-a risk factor for psychosis is associated with paranoia-may impact one's beliefs about the world and how beliefs are updated. We hypothesized that increased exposure to childhood maltreatment is... (Source: SafetyLit)
Source: SafetyLit - May 6, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
The impact of prolonged duration of untreated illness on clinical correlates in chronic schizophrenia: exploring the relationship with suicide risk - Zhang K, Wang C, Gou L, Li Y, Li C, Luo G, Zhang X.
OBJECTIVE: Studies on duration of untreated psychosis are common in patients with schizophrenia, but few studies have investigated the relationship between duration of untreated illness (DUI) and suicide, especially in patients with chronic schizophrenia. ... (Source: SafetyLit)
Source: SafetyLit - May 6, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Serious Mental Illness Tied to Multiple Physical Illnesses Serious Mental Illness Tied to Multiple Physical Illnesses
Serious mental illness, such as bipolar disorder or schizophrenia, is tied to a twofold increased risk for comorbid physical illnesses, new research showed.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - May 3, 2024 Category: Psychiatry Tags: Psychiatry News Source Type: news
Evaluating the Negative Symptoms of Schizophrenia in Clinical Trials - 08/16/2024
Information to learn about the Evaluating the Negative Symptoms of Schizophrenia in Clinical Trials. The purpose of the workshop is to discuss issues pertinent to conducting adequate development programs for a marketing application for a drug to treat the negative symptoms of schizophrenia. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 2, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Novel Drug Combo for Schizophrenia Works in Acute Psychosis
(MedPage Today) -- The investigational combination xanomeline-trospium (KarXT) was effective and well tolerated in individuals with schizophrenia who were experiencing acute psychosis, according to the randomized controlled phase III EMERGENT-3... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 1, 2024 Category: Psychiatry Source Type: news
Coping styles do not interact with the association between childhood trauma history and the immune-inflammatory phenotype of schizophrenia: findings from a cross-sectional study - Misiak B, Frydecka D, Piotrowski P, Rembacz K, Bielawski T, Samochowiec J, Tyburski E, Łaczmański, Pawlak E.
Adverse childhood experiences (ACEs) are a well-known risk factor of schizophrenia. Moreover, individuals with schizophrenia are likely to use maladaptive stress coping strategies. Although it has been reported that a history of ACEs might be associated wi... (Source: SafetyLit)
Source: SafetyLit - April 30, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Suicide attempts in schizophrenia - a large retrospective cohort study from a tertiary care psychiatry centre in India - Mamtani H, Pathak H, Sakhardande K, Gowda GS, Muliyala KP, Philip M, Moirangthem S, Reddi VSK, Varambally S.
This study aimed to identify the rates and associated correlates of SA in schizophrenia by reviewing a large cohort (n=500). Nearly... (Source: SafetyLit)
Source: SafetyLit - April 30, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Scientists restore brain cells impaired by a rare genetic disorder
A therapy that restores brain cells impaired by a rare genetic disorder may offer a strategy for treating conditions like autism, epilepsy, and schizophrenia. (Source: NPR Health and Science)
Source: NPR Health and Science - April 30, 2024 Category: Consumer Health News Authors: Jon Hamilton Source Type: news
Relationship of major depressive disorder and schizophrenia polygenic risk scores to suicide: a comparison between European and Asian ancestry populations - Otsuka I, Galfalvy H, Guo J, Akiyama M, Okazaki S, Terao C, Rujescu D, Turecki G, Hishimoto A, Mann JJ.
Psychiatric diagnosis rates in suicide decedents appear higher in European ancestry populations compared with East Asians. Shared genetic components exist between major depressive disorder (MDD)/schizophrenia (SCZ) and suicide, but no study has compared th... (Source: SafetyLit)
Source: SafetyLit - April 29, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
An exploration of depression and aggression among patients with schizophrenia in China rural community - Zhang S, Ouyang X, Yang K, Shen Y, Zheng S, Wang R, Sheng X, Ge M, Yang M, Zhou X.
PURPOSE: In schizophrenia, aggressive conduct is frequent. And depressed mood can also contribute to the occurrence of aggressive behaviors. The aim of this study was to investigate the risk factors for the occurrence of aggression in stable schizophrenia ... (Source: SafetyLit)
Source: SafetyLit - April 29, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Care for social isolation and loneliness in a case with late-onset delusional disorder - Kanemoto H, Kawasaki T.
Late-onset psychosis refers to the development of psychotic symptoms after the age of 40 and can encompass various conditions like schizophrenia, mood disorders with psychotic features, and delusional disorder. Non-pharmacological interventions are critica... (Source: SafetyLit)
Source: SafetyLit - April 24, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Physical Ills Often Plague People With Schizophrenia, Bipolar
TUESDAY, April 23, 2024 -- Severe mental illness can contribute to a decline in a person ’s physical health, with many chronic conditions slowly eroding their wellness, a new review finds.People with schizophrenia or bipolar disorder are more than... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 23, 2024 Category: General Medicine Source Type: news
Prevalence of multimorbidity in people with and without severe mental illness: a systematic review and meta-analysis - Halstead S, Cao C, H øgnason Mohr G, Ebdrup BH, Pillinger T, McCutcheon RA, Firth J, Siskind D, Warren N.
BACKGROUND: People with severe mental illness, such as schizophrenia-spectrum disorder and bipolar disorder, face poorer health outcomes from multiple chronic illnesses. Physical multimorbidity, the coexistence of two or more chronic physical conditions, a... (Source: SafetyLit)
Source: SafetyLit - April 22, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
