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Durable effect of imatinib and metronomic chemotherapy with capecitabine in pancreatic carcinoma
CONCLUSION: Metronomic chemotherapy, especially capecitabine added to the targeted therapy, imatinib, is a potentially useful treatment for PDC where no other options are available, especially those harbouring no mutation in the dominant four genes. Indeed, the absence of mutation with KIT amplification could be a potential marker for improved outcomes with targeted and metronomic therapy, which deserves further evaluation in a clinical trial setting.PMID:37138969 | PMC:PMC10151079 | DOI:10.3332/ecancer.2023.1535
Source: Ecancermedicalscience - May 4, 2023 Category: Cancer & Oncology Authors: Sana Al-Sukhun Karim Khalidi Source Type: research
