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Source: Clinical and Experimental Rheumatology
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Total 165 results found since Jan 2013.
Clinical features and pathology of respiratory failure due to inflammatory myopathy induced by immune checkpoint inhibitors
Clin Exp Rheumatol. 2021 Jun 22. Online ahead of print.NO ABSTRACTPMID:34251330
Source: Clinical and Experimental Rheumatology - July 12, 2021 Category: Rheumatology Authors: Yuriko Aratake Kaoru Obata Keisuke Nishimura Katsuro Shindo Source Type: research
Validation of the EULAR/ACR 2017 idiopathic inflammatory myopathy classification criteria in juvenile dermatomyositis patients.
CONCLUSIONS: The new EULAR/ACR criteria performed favourably in our JDM cohort especially with the probability cut-off of >62%.
PMID: 33337999 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - December 19, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Anti-Zo antibodies in Japanese myositis patients detected by a newly developed ELISA.
CONCLUSIONS: This is the first report of anti-Zo-positive IIM patients from Asia. Although Japanese patients with anti-Zo have a clinical phenotype similar to that of Caucasian patients, further large cohort studies are necessary to confirm the frequency of anti-Zo in Japanese IIM patients. Our newly developed ELISA should be validated for sensitivity and specificity in large cohorts.
PMID: 33124571 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - November 1, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Accumulation of autophagosome cargo protein p62 is common in idiopathic inflammatory myopathies.
CONCLUSIONS: p62 accumulation is a general response to muscle injury and not a specific marker for sIBM. Also, in sIBM, p62 RNA levels are decreased, suggesting that, in this disease, p62 aggregation is not due to overexpression.
PMID: 32896253 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - September 12, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Identification of a novel autoantibody against heat shock factor 1 in idiopathic inflammatory myopathy.
CONCLUSIONS: These data reveal anti-HSF1 as a new autoantibody associated with CAM in IIM. The autoimmunity against HSF1 may be involved in the immunopathogenesis of myositis.
PMID: 32141435 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - March 7, 2020 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy.
CONCLUSIONS: Lineblot seems to be an interesting tool for MSA detection in a clinical context, allowing the identification of clinical subtypes. However, considerable caution must be exercised in interpreting the results in case of low positive MSA signal intensity, discordant lineblot results and/or an incompatible IIF pattern.
PMID: 31287411 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - July 10, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
