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Molecules, Vol. 27, Pages 2737: Comparison of the Phytochemical Variation of Non-Volatile Metabolites within Mother Tinctures of Arnica montana Prepared from Fresh and Dried Whole Plant Using UHPLC-HRMS Fingerprinting and Chemometric Analysis
In this study, an untargeted metabolomics approach with UHPLC-HRMS/MS was used to cross-compare the phytochemical composition of mother tinctures of A. montana that were prepared from either fresh whole plant (fMT) matter or from oven-dried whole plant (dMT) matter. The multivariate data analysis showed significant differences between fMT and dMT. The dereplication of the HRMS and MS/MS spectra of the more discriminant compounds led to annotated quinic acid, dicaffeoyl quinic acids, ethyl caffeate, thymol derivatives and dehydrophytosphingosine, which were increased in fMT, while Amadori rearrangement products (ARP) and me...
Source: Molecules - April 24, 2022 Category: Chemistry Authors: Simon Duthen Alice Gad éa Pascal Trempat Naoual Boujedaini Nicolas Fabre Tags: Article Source Type: research

Development and Validation of Chromatographic Method for the Standardization of Homeopathic Formulation of Syzygium Cumini
CONCLUSION: Physicochemical analysis and the HPLC method for quantitative estimation of ellagic acid can be used to standardize a homeopathic formulation of Syzygium cumini.PMID:34020480 | DOI:10.1055/s-0041-1726019
Source: Homeopathy - May 21, 2021 Category: Complementary Medicine Authors: Rashmi Mishra Nandakishor Kotagale Milind Umekar Rajesh Sahu Amit Maliye Shailendra Gurav Source Type: research

Molecules, Vol. 26, Pages 2503: Artemisia abrotanum L. (Southern Wormwood) —History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications
Molecules, Vol. 26, Pages 2503: Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications Molecules doi: 10.3390/molecules26092503 Authors: Halina Ekiert Ewa Knut Joanna Świątkowska Paweł Klin Agnieszka Rzepiela Michał Tomczyk Agnieszka Szopa Artemisia abrotanum L. (southern wormwood) is a plant species with an important position in the history of European and Asian medicine. It is a species famous as a medicinal plant in Central Asia, Asia Minor, and in South-East and...
Source: Molecules - April 25, 2021 Category: Chemistry Authors: Halina Ekiert Ewa Knut Joanna Świątkowska Pawe ł Klin Agnieszka Rzepiela Micha ł Tomczyk Agnieszka Szopa Tags: Review Source Type: research

Scientific Papers and Patents on Substances with Unproven Effects. Part 2.
In conclusion, placebo therapies can be beneficial and ethically justifiable but it is not a sufficient reason to publish biased information. Importantly, placebo must be devoid of adverse effects, otherwise it is named pseudo-placebo. Therapeutic methods with unproven effects should be tested in high quality research shielded from the funding bias. Some issues discussed in this review are not entirely clear, and the arguments provided here can initiate a constructive discussion. PMID: 31424374 [PubMed - as supplied by publisher]
Source: Recent Patents on Drug Delivery and Formulation - August 20, 2019 Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research

Standardization of homeopathic mother tincture of Toxicodendron pubescens and correlation of its flavonoid markers with the biological activity.
CONCLUSIONS: This study validates a quantitative HPTLC method for standardization of homeopathic mother tincture of Rhus Tox and establishes quercitrin and rutin as markers corresponding its biological activity. Contents of quercitrin and rutin in T. pubescens mother tincture correlates with its anti-inflammatory and analgesic actions and the validated HPTLC method can be used in standardization of homeopathic mother tincture of T. pubescens. PMID: 26827997 [PubMed - in process]
Source: Homeopathy - February 1, 2016 Category: Complementary Medicine Authors: Jadhav HP, Chaudhari GG, Patil DD, Jadhav RB, Reddy NM, Shirkhedkar AA, Goyal SN, Patil CR Tags: Homeopathy Source Type: research