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Efficient antibacterial dextran-montmorillonite composite sponge for rapid hemostasis with wound healing.
Abstract Montmorillonite (MMT) powder, as the most effective hemostats in natural silicates, is restricted for commercial application due to its embolic effect. Until now, it's still a challenge to control the leakage of MMT and avoid its side-effects. Herein, poly aldehyde dextran (PDA)/MMT composite sponge (PM) with commendable tissue adhesion, antibacterial, and wound healing performances is developed for massive hemorrhage control. Based on the high degree of perfect synergism of PDA and MMT, the PM sponge can rapidly seal the wound, and promote cells aggregation and adhesion, whole coagulation system activati...
Source: International Journal of Biological Macromolecules - May 20, 2020 Category: Biochemistry Authors: Liu C, Liu C, Yu S, Wang N, Yao W, Liu X, Sun G, Song Q, Qiao W Tags: Int J Biol Macromol Source Type: research

SURGICEL & #194; & #174; Powder Absorbable Hemostat is used in surgeries.
SURGICEL® Powder Absorbable Hemostat is used for broad-surface oozing and stops bleeding fast. Unit is suitable for gynecologic, oncologic, cardiovascular and general procedure applications. Product offers bactericidal activity in vitro against MRSA, MRSE, VRE, PRSP, E Coli pathogens.This story is related to the following:Hemostats
Source: Industrial Newsroom - Health, Medical and Dental Supplies - January 10, 2018 Category: Medical Devices Source Type: news

Influences of mesoporous zinc-calcium silicate on water absorption, degradability, antibacterial efficacy, hemostatic performances and cell viability to microporous starch based hemostat
In this study, mesoporous zinc-calcium silicate (m-ZCS) was synthesized, and microporous starch (MS) based hemostatic agents of m-ZCS/MS composites for hemorrhage control was fabricated. The results showed that the incorporation of m-ZCS into MS significantly enhanced the water absorption and degradability of the composites, which were dependent on the m-ZCS content. Moreover, the composites with antibacterial property could inhibit the growth of Escherichia coli (E. coli) and the antibacterial ratios increased with the m-ZCS content. The in vitro coagulation evaluation by using activated partial thromboplastin time (APTT)...
Source: Materials Science and Engineering: C - March 17, 2017 Category: Materials Science Source Type: research