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The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
September 29, 2022 Edition-----The world seems to be lurching to be overwhelmed by issues around most of the major powers being in conflict for a real risk of a global recession affecting the UK, Europe, the US and much of Asia. We seem to be in some pretty difficult times right now …In OZ Parliament is now back after the death of the Queen and it will be interesting to see how things play out and what the Budget looks like in the face of an upcoming recession.-----Major Issues.-----https://www.afr.com/politics/federal/a-nation-shorn-of-britishness-is-still-waiting-for-the-republic-20220915-p5bi90A nation shorn of Britis...
Source: Australian Health Information Technology - September 29, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 2nd 2016
This study is the first CAR T-cell trial to infuse patients with an even mixture of two types of T cells (helper and killer cells, which work together to kill cancer). With the assurance that each patient gets the same mixture of cells, the researchers were able to come to conclusions about the effects of administering different doses of cells. In 27 of 29 participants whose responses were evaluated a few weeks after the infusion, a high-sensitivity test could detect no trace of their cancer in their bone marrow. The CAR T cells eliminated cancers anywhere in the body they appeared. Of the two participants who did n...
Source: Fight Aging! - May 1, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs