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Total 92237 results found since Jan 2013.
High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4
CONCLUSION: Circ-PALLD is highly expressed in heart failure and can be used as a novel molecular marker for chronic heart failure, and GATA4 may play important role in regulating its transcription. Circ-PALLD points a new direction for investigating the molecular mechanism of heart failure and may also serve as a potential therapeutic target for heart failure.PMID:37712274 | PMC:PMC10505580 | DOI:10.12122/j.issn.1673-4254.2023.08.14
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Huang Z Zeng J Li R Cai W He S Hu Source Type: research
MiR-301a-5p modulates parathyroid hormone secretion in secondary hyperparathyroidism possibly by regulating calcium-sensing receptor
CONCLUSION: MiR-301a-5p affects PTH secretion in SHPT possibly by regulating the expression of CaSR.PMID:37712273 | PMC:PMC10505570 | DOI:10.12122/j.issn.1673-4254.2023.08.13
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Liu L Qian P Li J Li S Huang W Yi S Liu W Wu Source Type: research
Curcumin suppresses proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells through the Keap1-Nrf2 pathway
CONCLUSION: Curcumin inhibits the proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells probably via the Keap1-Nrf2 signaling pathway.PMID:37712272 | PMC:PMC10505584 | DOI:10.12122/j.issn.1673-4254.2023.08.12
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Ren M Zou X Zhu W Xu G Liu J Sun F Fan C Zhang Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | PMC:PMC10505578 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Lipocalin 2 induces self-limited inhibition of osteoblast differentiation of mesenchymal stem cells
CONCLUSION: Lcn2 is essential for normal osteogenic differentiation of MSCs, but its overexpression and excessive secretion in aging induce self-limited inhibition of osteogenic differentiation of MSCs.PMID:37712270 | PMC:PMC10505573 | DOI:10.12122/j.issn.1673-4254.2023.08.10
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chen S Li Y Zhang W Yang T Wang Source Type: research
VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells
CONCLUSIONS: VDAC1 participates in HDM-induced chronic airway inflammation in bronchial asthma by causing ferroptosis of the airway epithelial cells.PMID:37712269 | PMC:PMC10505576 | DOI:10.12122/j.issn.1673-4254.2023.08.09
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Huang L Lin H Huang H Dong Source Type: research
ARHGAP21 inhibits epithelial-mesenchymal transition by inactivating the WNT signaling pathway in non-small cell lung cancer
CONCLUSION: ARHGAP21 downregulation can significantly promote the migration and metastatic ability of NSCLC possibly as a result of WNT signaling pathway activation, which reduces the ubiquitination of β-catenin by affecting the expressions of APC, GSK3β, and Axin.PMID:37712268 | PMC:PMC10505574 | DOI:10.12122/j.issn.1673-4254.2023.08.08
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Xie L Liu J Fang X Zhong J Lin F Chen Source Type: research
< em > Guizhi < /em > < em > Fuling < /em > Capsule inhibits migration and induces apoptosis of human ovarian cancer cells by regulating the NF- κB signaling pathway
CONCLUSION: GFC- medicated sera inhibits the migration ability of SKOV3/DDP cells possibly by promoting cell apoptosis and caspase 3 and CDH1 expressions, inhibiting CDH2 and NF-κB expressions, and regulating the expressions of NF-κB, CDH2 and CDH1 in the open chromatin.PMID:37712267 | PMC:PMC10505568 | DOI:10.12122/j.issn.1673-4254.2023.08.07
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Guo L Chen Q L ü R DU Q Luo Y Zhang H Bian L Han Source Type: research
Acetylcorynoline relieves 2, 4, 6-trinitrobenesulfonic acid-induced Crohn's disease-like colitis in mice by regulating intestinal epithelial cell apoptosis
CONCLUSION: Acetylcorynoline protects against TNBS-induced CDlike colitis in mice possibly by suppressing the activation of the PI3K/AKT signaling pathway, thereby inhibiting apoptosis of the intestinal epithelial cells.PMID:37712266 | PMC:PMC10505581 | DOI:10.12122/j.issn.1673-4254.2023.08.06
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Q Li J Huang Y Sun Y Xu L Wang X Zhang Y Wang Z Geng X Song L Zuo J Li J Hu Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | PMC:PMC10505577 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
< em > Erchen < /em > Decoction improves iron homeostasis in mice with non-alcoholic fatty liver disease by regulating iron transport capacity in the spleen
CONCLUSION: Erchen Decoction can alleviate high-fat diet-induced iron metabolism disorder by improving the iron ion transport ability of the spleen cells to delay the progression of NAFLD.PMID:37712264 | PMC:PMC10505571 | DOI:10.12122/j.issn.1673-4254.2023.08.04
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: G Deng H Jia Y Li J Li C Wu H Shi M Qin J Zhao C Liu Y Liao L Gao Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | PMC:PMC10505579 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy
CONCLUSION: DHM can improve motor function of PD mice probably by activating autophagy to inhibit pyroptosis and necroptosis and reduce neuroinflammation.PMID:37712262 | PMC:PMC10505583 | DOI:10.12122/j.issn.1673-4254.2023.08.02
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: M Zhang Y Zhang M Niu Y Zhu S Tong X Kou Source Type: research
Sivelestat sodium for treatment of patients with COVID-19-associated acute respiratory distress syndrome in intensive care unit: a single-center retrospective cohort study
CONCLUSION: Sivelestat sodium treatment is not correlated with the reduction of mortality or length of hospital stay, but is associated with reduced serum IL-6 level in patients with COVID-19-associated ARDS.PMID:37712261 | PMC:PMC10505566 | DOI:10.12122/j.issn.1673-4254.2023.08.01
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: M Luo H Hu Y Sun X Zhao Z Zeng Y Liu G Wu Source Type: research
Role of the physiologist in the COVID-19 pandemic
Adv Physiol Educ. 2023 Dec 1;47(4):755-756. doi: 10.1152/advan.00081.2023.NO ABSTRACTPMID:37703418 | DOI:10.1152/advan.00081.2023
Source: Adv Physiol Educ - September 13, 2023 Category: Universities & Medical Training Authors: Farheen Fatima Indla Yogananda Reddy Source Type: research
