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Outpatient Management of COVID-19: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):370-381.ABSTRACTNew COVID-19 variants of concern continue to develop. Incubation period, transmissibility, immune escape, and treatment effectiveness differ by variants of concern. Physicians should be aware that the characteristics of the predominant variants of concern determine aspects of diagnosis and treatment. Multiple testing modalities exist; the most appropriate testing strategy varies depending on the clinical scenario, with factors of test sensitivity, turnaround time, and the expertise required for specimen collection. Three types of vaccines are available in the United States,...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Anthony M Cheng Emily Dollar Heather Angier Source Type: research

US National Institutes of Health Prioritization of SARS-CoV-2 Variants
Emerg Infect Dis. 2023 Apr 13;29(5). doi: 10.3201/eid2905.221646. Online ahead of print.ABSTRACTSince late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and infection. The Early Detection group is one of the constituent groups of the US National Institutes of Health National Institute of Allergy and Infectious Diseases SARS-CoV-2 Assessment of Viral Evolution program. The group uses bioinformatic methods to monitor the emergence, spread, and potential phenotypic...
Source: Emerging Infectious Diseases - April 13, 2023 Category: Infectious Diseases Authors: Sam Turner Arghavan Alisoltani Debbie Bratt Liel Cohen-Lavi Bethany L Dearlove Christian Drosten Will M Fischer Ron A M Fouchier Ana Silvia Gonzalez-Reiche Lukasz Jaroszewski Zain Khalil Eric LeGresley Marc Johnson Terry C Jones Barbara M ühlemann David Source Type: research

Outpatient Management of COVID-19: Rapid Evidence Review
Am Fam Physician. 2023 Apr;107(4):370-381.ABSTRACTNew COVID-19 variants of concern continue to develop. Incubation period, transmissibility, immune escape, and treatment effectiveness differ by variants of concern. Physicians should be aware that the characteristics of the predominant variants of concern determine aspects of diagnosis and treatment. Multiple testing modalities exist; the most appropriate testing strategy varies depending on the clinical scenario, with factors of test sensitivity, turnaround time, and the expertise required for specimen collection. Three types of vaccines are available in the United States,...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Anthony M Cheng Emily Dollar Heather Angier Source Type: research