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Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons. Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Where Is the Boundary to Augment Life?
Cloning, CRISPR and gene editing, synthetic life forms, and longevity. The latest scientific discoveries are able to offset the natural order of human existence and meddle with sacred questions of life and death. Even so, does gaining insight into the secrets of being mean it should also be put into practice? Are we aware of the consequences? Where are the boundaries to augment life? Life, death and the coin for Charon the Ferryman In Japanese folklore, the Shinigami, gods or spirits of death came to the persons who were destined to die and invited them over the threshold of life and death. In ancient Egypt, Anubis, having...
Source: The Medical Futurist - July 28, 2018 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization artificial intelligence augmentation bioethical cloning CRISPR death future gene editing Health Healthcare life longevity research synthetic life Source Type: blogs

Fight Aging! Newsletter, September 19th 2016
In conclusion, we found that IS status was associated with a significant increase in Hannum DNA methylation, likely as a consequence of the accumulation of cardiovascular risk factors, and near signification with Horvath method. Patients with IS were biologically older than controls, a difference that was more obvious in young stroke. This could open up the possibility of useful new biomarker of stroke risk. Latest Headlines from Fight Aging! A Profile of Kelsey Moody and Ichor Therapeutics https://www.fightaging.org/archives/2016/09/a-profile-of-kelsey-moody
Source: Fight Aging! - September 18, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Twerking Disease: The Definitive Medical Resource For Doctors.
This study was published in Time magazine so it must be true.  In addition, the story was picked up by 95.8 THE BONE and was described by a self proclaimed expert twerker jockey between songs about booty slappin' and G-thangs.      EXERCISE Studies have shown most folks watching Richard Simmons in "Twerking to the Oldies" have been cured of their twerking addiction.      MIRROR THERAPY Consider buying a full length wall mirror for full therapeutic effect.  Alternatively, take a video of yourself twerking while checking yourself out in a mirror, put it on YouTube and let ever...
Source: The Happy Hospitalist - September 7, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs