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Vaccination: AIDS Vaccine
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Total 17 results found since Jan 2013.
Role of Low-Risk HPV PCR Monoinfection in Screening for HSIL and Anal Cancer in Men Who Have Sex with Men Living with HIV
Int J Mol Sci. 2023 Mar 15;24(6):5642. doi: 10.3390/ijms24065642.ABSTRACTTo determine the value of low-risk human papillomavirus (HPV) PCR to screen for "high-grade anal squamous intraepithelial lesion and anal cancer" (HSIL-plus), rate of patients with low-grade anal squamous intraepithelial lesion (LSIL) progressing to HSIL-plus, and progression-related factors. Prospective, longitudinal study of consecutive MSM-LHIV attended between May 2010 and December 2021 and followed for 43 months (IQR: 12-76). HIV-related variables were gathered at baseline, performing anal cytology for HPV detection/genotyping, thin-layer cytolog...
Source: Anal Sci - March 29, 2023 Category: Chemistry Authors: Carmen Mar ía García-Martínez Inmaculada Calle-G ómez Javier L ópez-Hidalgo Patricia G ómez-Ronquillo Mohamed Omar-Mohamed Balgahata Carmen Hidalgo-Tenorio Source Type: research
Computational approaches in discovery and development of therapeutic and prophylactic agents for viral diseases
Curr Top Med Chem. 2022 Oct 19. doi: 10.2174/1568026623666221019110334. Online ahead of print.ABSTRACTOver the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics and prophylactics. Computational drug and vaccine discovery have evolved at a breakneck pace over the years. Some interesting examples of computational drug discovery are anti-AIDS drugs, where HIV protease and reverse transcriptase have been targeted by agents developed using computatio...
Source: Current Topics in Medicinal Chemistry - October 24, 2022 Category: Chemistry Authors: Anand Gaurav Neetu Agrawal Mayasah Al-Nema Vertika Gautam Source Type: research
Computer Aided Reverse Vaccinology: A Game-changer Approach for Vaccine Development
Comb Chem High Throughput Screen. 2022 Sep 30. doi: 10.2174/1386207325666220930124013. Online ahead of print.ABSTRACTOne of the most dynamic approaches in biotechnology is reverse vaccinology, which plays a huge role in today's developing vaccines. It has the capability of exploring and identifying the most potent vaccine candidate in a limited period of time. The first successful novel approach of reverse vaccinology was observed in Neisseria meningitidis serogroup B, which has revolutionised the whole field of computational biology. In this review, we have summarized the application of reverse vaccinology for different i...
Source: Combinatorial Chemistry and High Throughput Screening - October 6, 2022 Category: Chemistry Authors: Poornima Srivastava Chakresh Kumar Jain Source Type: research
Neglected Tropical Diseases (NTDs) and COVID-19 pandemic in Africa: Special focus on control strategies
Comb Chem High Throughput Screen. 2022 Apr 27. doi: 10.2174/1386207325666220427123349. Online ahead of print.ABSTRACTNeglected Tropical Diseases (NTDs) are a group of twenty (20) chronic, communicable, infectious diseases endemic to the tropics and sub-tropics climate countries which are intimately associated with poverty, poor sanitation, limited clean water, and healthcare delivery; and dwellers live in proximity to pathogens and diseases vectors. The pathogens are protozoans, bacteria, helminths, fungi, and viruses. NTDs currently affects about one billion people globally, out of which 500 million are Africans living in...
Source: Combinatorial Chemistry and High Throughput Screening - May 1, 2022 Category: Chemistry Authors: Abdullahi Tunde Aborode Emmanuel Adebowale Fajemisin Emmanuel Ademola Aiyenuro Muhammad Alakitan Matthew Olaide Ariwoola Jegede Oluwatoyin Imisioluwa Raheemt Rafiu Athanasios Alexiou Source Type: research
