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Procedure: Skin Biopsy
Therapy: Immunotherapy
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Total 82 results found since Jan 2013.
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Leprosy rash precipitated by immunotherapy for suspected inflammatory neuropathy
We describe a 38-year-old woman with a 4-year history of progressive numbness of the left hand incorrectly diagnosed as multifocal acquired demyelinating sensory and motor neuropathy on the basis of clinical and neurophysiological findings. Treatment with empirical weekly corticosteroid followed by intravenous immunoglobulin resulted in the sudden development of a widespread rash; we then diagnosed borderline lepromatous leprosy on skin biopsy. We postulate that the immune treatments induced a temporary state of immune tolerance followed by a rebound of a T cell-mediated immune response resulting in a type 1 immunological ...
Source: Practical Neurology - November 25, 2022 Category: Neurology Authors: Almond Leung Brendan John Arnold Timothy Oliver Hodgson Nicholas John Cutfield Source Type: research
Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline - Update 2022
Eur J Cancer. 2022 Jun 19;171:203-231. doi: 10.1016/j.ejca.2022.03.043. Online ahead of print.ABSTRACTMerkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all cutaneous malignancies. It is found predominantly in white populations and risk factors include advanced age, ultraviolet exposure, male sex, immunosuppression, such as AIDS/HIV infection, haematological malignancies or solid organ transplantation, and Merkel cell polyomavirus infection. MCC is an aggressive tumour with 26% of cases presenting lymph node involvement at diagnosis and 8% with distant metastases. Five-year overall survival r...
Source: Cancer Control - June 22, 2022 Category: Cancer & Oncology Authors: Marie-L éa Gauci Cynthia Aristei Jurgen C Becker Astrid Blom Veronique Bataille Brigitte Dreno Veronique Del Marmol Ana M Forsea Maria C Fargnoli Jean-Jacques Grob Fabio Gomes Axel Hauschild Christoph Hoeller Catherine Harwood Nicole Kelleners-Smeets Rol Source Type: research
Fight Aging! Newsletter, May 30th 2022
In conclusion, fisetin supplementation may be a novel strategy to target excess cellular senescence and thereby reduce mitochondrial ROS to improve NO-mediated endothelial function with aging.
Exercise Upregulates BDNF Expression to Promote Dopamine Release and Brain Function
https://www.fightaging.org/archives/2022/05/exercise-upregulates-bdnf-expression-to-promote-dopamine-release-and-brain-function/
Researchers have in the past shown that exercise results in greater amounts of BDNF, which in turn promotes neurogenesis. Here, this line of research is extended to show that exercise results in an increas...
Source: Fight Aging! - May 29, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Neurosurgical management of patients with neurocutaneous melanosis: a systematic review
CONCLUSIONS: Current management of NCM includes CSF shunting to reduce intracranial pressure, surgery, chemotherapy, radiotherapy, immunotherapy, and palliative care. Neurosurgical intervention can aid in the diagnosis of NCM through tissue biopsy and resection of lesions with surgical decompression. Further evidence is required to establish the clinical outcomes of this rare entity and to describe the diverse spectrum of intracranial and intraspinal abnormalities present.PMID:35535823 | DOI:10.3171/2022.2.FOCUS21791
Source: Neurosurgical Focus - May 10, 2022 Category: Neurosurgery Authors: Raphia K Rahman Neil Majmundar Hira Ghani Ali San Monika Koirala Avi A Gajjar Amy Pappert Catherine A Mazzola Source Type: research
