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Stereotactic body radiation therapy for primary kidney cancer
Cancer Radiother. 2023 Aug 3:S1278-3218(23)00136-1. doi: 10.1016/j.canrad.2023.06.022. Online ahead of print.ABSTRACTThe incidence of primary renal cancer is increasing, particularly in elderly patients who may have comorbidities and/or a surgical contraindications. Stereotactic body radiotherapy has primarily been evaluated retrospectively to date. The most commonly used dose schedules are 40Gy in five fractions, 42Gy in three fractions, and 26Gy in one fraction. The results in terms of local control and toxicity are very encouraging. The advantages of stereotactic body radiotherapy compared to thermal ablative treatments...
Source: Cancer Radiotherapie - August 5, 2023 Category: Cancer & Oncology Authors: L Abancourt J Le Gu évelou A Taillez A Vu R de Crevoisier S Supiot C Hennequin O Chapet P Blanchard X Mirabel É Lartigau D Pasquier Source Type: research

Efficacy of ketamine mouthwash in the management of oral and pharyngeal toxicity associated with head and neck chemoradiotherapy: protocol for a phase II, Simon's two-stage trial
BMJ Open. 2023 Apr 11;13(4):e064809. doi: 10.1136/bmjopen-2022-064809.ABSTRACTINTRODUCTION: Curative intent treatment of head and neck cancer (HNC) is frequently radiation therapy over 7 weeks with concurrent chemotherapy. This regimen is effective but carries a burden of toxicity leading to severe pain and treatment breaks portending inferior outcomes. Conventional palliation methods include opioids, anticonvulsants and local anaesthetics. Breakthrough toxicities are nevertheless ubiquitous and present an urgent unmet need. Ketamine is an inexpensive drug with mechanisms of analgesia outside the opioid pathway including N...
Source: Cancer Control - April 11, 2023 Category: Cancer & Oncology Authors: Daniel Koffler Jacob Eckstein Joseph Herman Diana Martins-Welch Nagashree Seetharamu Maged Ghaly Nina Kohn Louis Potters Douglas Frank Kevin Sullivan Bhupesh Parashar Source Type: research

Rapport de cas Surgical retrieval of a migrated vascular access port catheter in a dog
Can Vet J. 2023 Apr;64(4):351-355.ABSTRACTA 4-year-old spayed female Boston terrier was diagnosed with a suspected meningioma involving the optic chiasm and resulting in vision loss. A vascular access port (VAP) was placed in the left medial saphenous vein to facilitate frequent anesthetic episodes for radiation therapy. Five days after placement, the VAP was nonfunctional with the silicone catheter still intact. During VAP removal surgery, it was discovered that the silicone catheter had migrated. Intraoperative focal ultrasound could not identify the migrated catheter within the pelvic limb. Thoracic computed tomography ...
Source: The Canadian Veterinary Journal - April 3, 2023 Category: Veterinary Research Authors: Sheena W Wong Aylin Atilla Jasmine Gu Vivian C Fan Kathleen A Linn Source Type: research

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