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Procedure: Kidney Transplant

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Total 48268 results found since Jan 2013.

Malignancies after pediatric solid organ transplantation
AbstractAs life expectancy among pediatric solid organ transplant recipients (SOTRs) improves, the risk of comorbid conditions such as malignancy post-transplantation has also increased. SOTRs are at elevated risks of post-transplantation lymphoproliferative disorders (PTLDs), and skin and solid cancers. PTLDs typically occur early following transplantation, while skin and solid cancers frequently arise in young adulthood (25 –40 years). By 30 years following transplantation, 26–41% of pediatric SOTRs have developed cancer. Different risk factors exist for PTLD, and skin and solid cancers, which are modified by cumulat...
Source: Pediatric Nephrology - July 6, 2021 Category: Urology & Nephrology Source Type: research

Assessment and management of obesity and metabolic syndrome in children with CKD stages 2 –5 on dialysis and after kidney transplantation—clinical practice recommendations from the Pediatric Renal Nutrition Taskforce
We present CPRs for the assessment and management of O&MS in children with CKD stages 2 –5, on dialysis and after kidney transplantation. We address the risk factors and diagnostic criteria for O&MS and discuss their management focusing on non-pharmacological treatment management, including diet, physical activity, and behavior modification in the context of age and CKD stage. The statements have been graded using the American Academy of Pediatrics grading matrix. Statements with a low grade or those that are opinion-based must be carefully considered and adapted to individual patient needs based on the clinical ...
Source: Pediatric Nephrology - August 10, 2021 Category: Urology & Nephrology Source Type: research

Associations among erythropoietic, iron-related, and FGF23 parameters in pediatric kidney transplant recipients
ConclusionOur study provides further insight into factors potentially associated with erythropoiesis in pediatric kidney transplant recipients.Graphical abstractA higher resolution version of the Graphical abstract is available as Supplementary information
Source: Pediatric Nephrology - September 17, 2021 Category: Urology & Nephrology Source Type: research

Advances in proteomic profiling of pediatric kidney diseases
AbstractChronic kidney disease  (CKD) can progress to kidney failure and require dialysis or transplantation, while early diagnosis can alter the course of disease and lead to better outcomes in both pediatric and adult patients. Significant CKD comorbidities include the manifestation of cardiovascular disease, heart failure, co ronary disease, and hypertension. The pathogenesis of chronic kidney diseases can present as subtle and especially difficult to distinguish between different glomerular pathologies. Early detection of adult and pediatric CKD and detailed mechanistic understanding of the kidney damage can be helpfu...
Source: Pediatric Nephrology - February 26, 2022 Category: Urology & Nephrology Source Type: research

Immunosuppressive drugs and associated complications in abdominal organ transplantation
Purpose of review Intensive care management of patients who have undergone organ transplantation of liver, small bowel, pancreas, and/or kidney requires a basic knowledge of immunosuppression principles and the management of immunosuppressive medications. This review highlights the core principles of immunosuppression management in abdominal organ transplantation with a focus on complications arising from immunosuppressive drugs, both in the immediate postoperative period and in long-term usage. Recent findings The general principles of management of immunosuppression in the abdominal organ transplant population...
Source: Current Opinion in Critical Care - March 8, 2022 Category: Nursing Tags: GASTROINTESTINAL SYSTEM: Edited by Julia Wendon Source Type: research

Congenital bilateral iliac vein anomalies in a Nigerian pediatric kidney transplant recipient: A case report and literature review
This article presents the case of an 11-year-old boy with end-stage renal disease who had kidney transplantation (KT). At presentation, he was found to have a large superficial vein running from the left groin over the suprapubic area. The arterial pulsation of both lower limbs was preserved, and there was no pedal edema. Contrast-enhanced computed tomography scan revealed aplasia of the right common iliac vein, stenosis of the left common iliac vein, and marked dilatation of the left external and internal iliac veins. There were also varicosity of numerous pelvic veins and a collateral vein draining the right lower limb. ...
Source: Annals of African Medicine - March 18, 2022 Category: African Health Authors: Martin Chukwudum Igbokwe Kester O Maduadi Olalekan Olayinka Olatise Abayomi Aremu Vasanth Revanur Source Type: research

Encouraging outcomes of using a small-donor single graft in pediatric kidney transplantation
ConclusionIn a specialized transplant center, the use of a single small pediatric donor kidney for transplantation is as successful as bigger pediatric or adult living donors, after 5  years of follow-up.Graphical abstractA higher resolution version of the Graphical abstract is available as Supplementary information.
Source: Pediatric Nephrology - April 21, 2022 Category: Urology & Nephrology Source Type: research

Effects of pediatric chronic kidney disease and its etiology on tissue sodium concentration: a pilot study
ConclusionsDepending on etiology, pediatric CKD was associated with either increased (glomerular disease) or reduced (tubular disorders) tissue [Na+] compared with healthy controls.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information.
Source: Pediatric Nephrology - June 2, 2022 Category: Urology & Nephrology Source Type: research

SARS-CoV-2 Infection in Pediatric Solid Organ Transplant Recipients: A Single Center Observation
Conclusions: Early in the pandemic, COVID-19 disease was mostly mild in pediatric SOT recipients with no rejection, patient death, or graft loss observed.
Source: Journal of Pediatric Gastroenterology and Nutrition - September 1, 2022 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

An ethical analysis of obesity as a contraindication of pediatric kidney transplant candidacy
AbstractThe inclusion of body mass index (BMI) as a criterion for determining kidney transplant candidacy in children raises clinical and ethical challenges. Childhood obesity is on the rise and common among children with kidney failure. In addition, obesity is reported as an independent risk factor for the development of CKD and kidney failure. Resultantly, more children with obesity are anticipated to need kidney transplants. Most transplant centers around the world use high BMI as a relative or absolute contraindication for kidney transplant. However, use of obesity as a relative or absolute contraindication for pediatr...
Source: Pediatric Nephrology - December 19, 2022 Category: Urology & Nephrology Source Type: research

Physical performance capacity after pediatric kidney transplant and clinical parameters associated with physical performance capacity
ConclusionThe physical performance of pediatric kidney transplant recipients is reduced, especially in those with congenital nephrotic syndrome. Clinical parameters, including graft function, did not predict physical performance capacity, suggesting that the reduced physical performance seems to be of multivariable cause.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information
Source: Pediatric Nephrology - March 30, 2023 Category: Urology & Nephrology Source Type: research

Emulation of the control cohort of a randomized controlled trial in pediatric kidney transplantation with Real-World Data from the CERTAIN Registry
ConclusionsIn conclusion, usage of Real-World Data from patient registries such as CERTAIN to emulate the control cohort of an RCT is feasible and could facilitate the conduct of clinical trials in pediatric kidney transplantation.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information
Source: Pediatric Nephrology - March 30, 2023 Category: Urology & Nephrology Source Type: research

Left ventricular hypertrophy in pediatric patients on maintenance dialysis: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
ConclusionsLVH is prevalent in pediatric patients at dialysis initiation and remains prevalent during follow-up. Hypertension is the strongest risk factor for LVH in children on maintenance dialysis.Graphical AbstractA higher resolution version of the Graphical abstract is available asSupplementary information
Source: Pediatric Nephrology - May 2, 2023 Category: Urology & Nephrology Source Type: research

Angiotensin II type 1 receptor antibodies and native kidney function in pediatric liver and intestinal transplant recipients
ConclusionsAT1R-Ab positivity was not associated with a decline in eGFR or hypertension in pediatric liver and intestinal transplant recipients. Further studies are needed using other markers of kidney function, such as cystatin C, to validate this finding.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information
Source: Pediatric Nephrology - July 11, 2023 Category: Urology & Nephrology Source Type: research