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Procedure: Liver Transplant

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Total 21872 results found since Jan 2013.

Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study
In conclusion, everolimus with reduced CNI improved renal function while maintaining antirejection potency in pediatric liver transplant patients but safety outcomes suggest that patients were overimmunosuppressed.
Source: Pediatric Transplantation - July 17, 2017 Category: Transplant Surgery Authors: Rainer Ganschow, Bo ‐Goran Ericzon, Anil Dhawan, Khalid Sharif, El‐Djouher Martzloff, Barbara Rauer, Jennifer Ng, Patricia Lopez Tags: ORIGINAL ARTICLE Source Type: research

Clinical relevance of a CD4+ T cell immune function assay in the diagnosis of infection in pediatric living-donor liver transplantation.
Authors: Liu W, Wang K, Zhao YH, Song GP, Gao W, Li DH Abstract The aim of the present study was to investigate the potential of the Immuknow immune cell function assay for the diagnosis of infection after pediatric living-donor liver transplantation (LDLT). Based on clinical data obtained following liver transplantation, 66 patients were divided into infection (n=28) and non-infection (n=38) groups. The following factors were considered in the present analysis: Primary disease, lymphocyte count, tacrolimus plasma concentration/dose (C0/D) ratio, CD4+ T lymphocyte ATP levels, at pre-transplant stage and at weeks 1-...
Source: Experimental and Therapeutic Medicine - October 12, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research

Admission Characteristics Identify Risk of Pediatric Acute-on Liver Failure
Objectives: Acute-on-chronic liver failure (ACLF) is well-studied in adults and characterized by decompensated cirrhosis, multi-organ failure, and early mortality. Studies of ACLF in children are limited. We sought to characterize the prevalence and clinical factors associated with pediatric ACLF (PACLF). Methods: A retrospective review of children 3 months to 18 years listed for liver transplantation and hospitalized for decompensated cirrhosis between January 2007 and December 2017 at a single pediatric hospital. Primary outcome was the development of PACLF, characterized as failure of at least 1 extrahepatic organ ...
Source: Journal of Pediatric Gastroenterology and Nutrition - May 24, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Admission Characteristics Identify Risk of Pediatric Acute-on-Chronic Liver Failure
Objectives: Acute-on-chronic liver failure (ACLF) is well-studied in adults and characterized by decompensated cirrhosis, multi-organ failure, and early mortality. Studies of ACLF in children are limited. We sought to characterize the prevalence and clinical factors associated with pediatric ACLF (PACLF). Methods: A retrospective review of children 3 months to 18 years listed for liver transplantation and hospitalized for decompensated cirrhosis between January 2007 and December 2017 at a single pediatric hospital. Primary outcome was the development of PACLF, characterized as failure of at least 1 extrahepatic organ ...
Source: Journal of Pediatric Gastroenterology and Nutrition - June 1, 2020 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Clinical relevance of donor-specific human leukocyte antigen antibodies after pediatric liver transplantation
Exp Ther Med. 2021 Aug;22(2):867. doi: 10.3892/etm.2021.10299. Epub 2021 Jun 13.ABSTRACTDonor-specific human leukocyte antigen (HLA) antibodies (DSAs) have a significant role in graft survival after pediatric liver transplantation. To understand the significance of DSAs, a retrospective cohort study of 48 pediatric liver transplant recipients with posttransplant serum samples that were analyzed for DSAs was performed. According to their test results, the recipients were divided into a DSA-positive group and a DSA-negative group. Postoperative liver transplantation biopsies were performed in patients with abnormal liver fun...
Source: Experimental and Therapeutic Medicine - July 1, 2021 Category: General Medicine Authors: Wei Liu Kai Wang Yan-Li Xiao Chun Liu Wei Gao Dai-Hong Li Source Type: research

THE IMPACT OF LOW RECIPIENT WEIGHT ≤ 7Kg ON LONG-TERM OUTCOMES IN 1078 PEDIATRIC LIVING DONOR LIVER TRANSPLANTATIONS
Many factors may influence the timing of liver transplantation (LT), including age of the child, etiology of the underlying liver disease, patient quality of life, and past medical and surgical history [1]. Infants who require LT represent a treatment challenge because chronic liver disease at this early age affects the child's growth and development during a critical phase. Furthermore, the severity of liver disease in these patients may be different from that of older children [2].
Source: Journal of Pediatric Surgery - May 22, 2022 Category: Surgery Authors: Jo ão Seda Neto, Paulo Chapchap, Flavia H. Feier, Renata Pugliese, Rodrigo Vincenzi, Marcel R Benavides, Karina Roda, Mário Kondo, Eduardo A. Fonseca Source Type: research

Cirrhotic cardiomyopathy and hepatopulmonary syndrome: Prevalence and prognosis in a series of patients
Summary: Hepatopulmonary syndrome (HPS) is of prognostic value in patients awaiting for orthotopic liver transplantation (OLT), but little is known about the effect of cirrhotic cardiomyopathy (CCM). The aim of the present study was to estimate the prevalence and possible relation between respiratory and cardiac abnormalities in a same series of patients awaiting OLT. Special attention was paid to the prognostic value of CCM in comparison to HPS.Eighty-three patients were included (19 females, 64 males; 52.1 ± 10.0 yrs). All had lung function testing with arterial blood gases and echocardiographic evaluation at rest wit...
Source: Respiratory Medicine CME - April 23, 2013 Category: Respiratory Medicine Authors: Irina Enache, Monique Oswald-Mammosser, Marie-Lorraine Woehl-Jaegle, François Habersetzer, Paola Di Marco, Anne Charloux, Stéphane Doutreleau Tags: Critical Care Source Type: research