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Procedure: Perfusion

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Clearance of Indocyanine Green in Severe Pediatric Burns
BACKGROUND Clearance of indocyanine green dye (ICGc) reflects sinusoidal perfusion and hepatocyte cell membrane function. Thus, ICGc is a reflection of the functional reserve of intact hepatocytes. The purpose of this study was to identify predictors of ICGc in severely burned children during the acute hospitalization and at the time of discharge from the intensive care unit (ICU). A secondary aim was to determine the relationship between liver size and patient ICGc. METHODS Twenty-six children (0.8–17 years old) with 35% or greater total body surface area burned (%TBSA-B) were included. Assessment of ICGc (in milli...
Source: The Journal of Trauma: Injury, Infection, and Critical Care - April 26, 2019 Category: Orthopaedics Tags: ORIGINAL ARTICLES Source Type: research

Mean Arterial Pressure and Discharge Outcomes in Severe Pediatric Traumatic Brain Injury
ConclusionsIn children with severe TBI, a single MAP  <  10th percentile during the first 12 h after Pediatric Intensive Care Unit admission was associated with poor discharge outcome. Lowest MAP percentile during the first 12 h was moderately predictive of poor discharge outcome. Lowest MAP percentile was more strongly associated with outcome than l owest SBP percentile but had slightly lower predictive ability than SBP.
Source: Neurocritical Care - October 27, 2020 Category: Neurology Source Type: research

Simultaneous Imaging of Lung Perfusion and Glucose Metabolism in COVID-19 Pneumonia
Am J Respir Crit Care Med. 2021 Feb 26. doi: 10.1164/rccm.202007-2944IM. Online ahead of print.NO ABSTRACTPMID:33636089 | DOI:10.1164/rccm.202007-2944IM
Source: American Journal of Respiratory and Critical Care Medicine - February 26, 2021 Category: Respiratory Medicine Authors: Celso Dario Ramos Alins P Fernandes Stephan P M Souza Mariana Fujiwara Natalia Tobar Sergio S J Dertkigil Maria Em ília S Takahashi Eduardo S L Gon çales Plinio Trabasso Denise E Zantut-Wittmann Source Type: research

Continuous non-invasive measurement of urethral perfusion to assess microcirculation: A pilot study in cardiac surgery patients
Publication date: Available online 29 April 2021Source: Anaesthesia Critical Care & Pain MedicineAuthor(s): Laure Cazenave, Arnaud Ferraris, Matthias Jacquet-Lagrèze, Bernard Allaouchiche, Jean-Luc Fellahi
Source: Anaesthesia, Critical Care and Pain Medicine - April 29, 2021 Category: Anesthesiology Source Type: research

Renal Microcirculation and Function in a Pig Model of Hemorrhagic Shock Resuscitation with Norepinephrine
CONCLUSION: In pigs with hemorrhagic shock, resuscitation with a combination of NE and fluid restored kidney microcirculation and oxygenation, as well as renal function, in a manner comparable to fluid resuscitation alone and without differences between the two NE doses. NE administration led to a fluid volume sparing effect with subsequently less hemodilution.PMID:35394403 | DOI:10.1164/rccm.202109-2120OC
Source: American Journal of Respiratory and Critical Care Medicine - April 8, 2022 Category: Respiratory Medicine Authors: Nicolas Libert Elisabeth Laemmel Anatole Harrois Philippe Laitselart Benjamin Bergis Pierre Isnard Fabiola Terzi Benoit Decante Olaf Mercier Eric Vicaut Jacques Duranteau Source Type: research

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two < em > F508del < /em > Alleles
CONCLUSIONS: Our data demonstrate that improvement of CFTR function by ELX/TEZ/IVA improves lung ventilation and abnormalities in lung morphology including airway mucus plugging and wall thickening in adolescent and adult patients with CF and one or two F508del alleles in a real-world, post-approval setting.PMID:35536314 | DOI:10.1164/rccm.202201-0219OC
Source: American Journal of Respiratory and Critical Care Medicine - May 10, 2022 Category: Respiratory Medicine Authors: Simon Y Graeber Diane M Renz Mirjam Stahl Sophia T Pallenberg Olaf Sommerburg Lutz Naehrlich Julian Berges Martha Dohna Felix C Ringshausen Felix Doellinger Constanze Vitzthum Jobst R öhmel Christine Allomba Susanne H ämmerling Sandra Barth Claudia R ü Source Type: research

Redistribution of Perfusion by Prone Positioning Improves Shunt in a Patient with Unilateral Lung Injury
Am J Respir Crit Care Med. 2022 Aug 29. doi: 10.1164/rccm.202206-1060IM. Online ahead of print.NO ABSTRACTPMID:36036926 | DOI:10.1164/rccm.202206-1060IM
Source: American Journal of Respiratory and Critical Care Medicine - August 29, 2022 Category: Respiratory Medicine Authors: Douglas Slobod Elena Spinelli Gaetano Scaramuzzo Alfredo Lissoni Giacomo Grasselli Tommaso Mauri Source Type: research

Comparison of Bedside and Video-Based Capillary Refill Time Assessment in Children
Objectives Capillary refill time (CRT) to assess peripheral perfusion in children with suspected shock may be subject to poor reproducibility. Our objectives were to compare video-based and bedside CRT assessment using a standardized protocol and evaluate interrater and intrarater consistency of video-based CRT (VB-CRT) assessment. We hypothesized that measurement errors associated with raters would be low for both standardized bedside CRT and VB-CRT as well as VB-CRT across raters. Methods Ninety-nine children (aged 1–12 y) had 5 consecutive bedside CRT assessments by an experienced critical care clinician fo...
Source: Pediatric Emergency Care - October 1, 2022 Category: Emergency Medicine Tags: Original Articles Source Type: research