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Procedure: Transplants

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Total 141452 results found since Jan 2013.

Characteristics and outcomes of patients with a haematological malignancy admitted to the intensive care unit for a neurological event.
CONCLUSIONS: Patients with a history of haematological malignancy presenting with a critical neurological event have comparable survival rates with other patients with a haematologic malignancy admitted to the ICU. Our findings suggest that restrictions in ICU care are not justified for this patient population. PMID: 26640063 [PubMed - in process]
Source: Critical Care and Resuscitation - December 11, 2015 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Bone Marrow-derived Cells Contribute to Pathogenesis of Pulmonary Arterial Hypertension.
CONCLUSIONS: Our data show that BM cells played key role in PAH pathogenesis and given that the transplanted BM cells were able to drive the lung phenotype. Furthermore the specific cell types involved were derived from HSCs and exhibit dysfunction long before the development of lung pathology. PMID: 26651104 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 9, 2015 Category: Respiratory Medicine Authors: Yan L, Chen X, Talati M, Nunley BW, Gladson S, Blackwell T, Cogan J, Austin E, Wheeler F, Loyd J, West J, Hamid R Tags: Am J Respir Crit Care Med Source Type: research

Haemoptysis and Progressive Dyspnoea in a 67-year-old Woman with History of Renal Transplantation.
PMID: 26681504 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 17, 2015 Category: Respiratory Medicine Authors: Lococo F, Montanari G, Mengoli MC, Ferrari F, Spagnolo P, Rossi G Tags: Am J Respir Crit Care Med Source Type: research

Organ donation in adults: a critical care perspective
Conclusions Organ donation should be offered as a routine component of the end-of-life care plan of every patient dying in the ICU where appropriate, and intensivists are the key professional in this process.
Source: Intensive Care Medicine - January 11, 2016 Category: Intensive Care Source Type: research

Diastolic Dysfunction Increases the Risk of Primary Graft Dysfunction After Lung Transplantation.
CONCLUSIONS: Differences in left ventricular diastolic function may contribute to the development of PGD. Future trials are needed to determine whether optimization of left ventricular diastolic function will modify the risk of PGD. PMID: 26745666 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 8, 2016 Category: Respiratory Medicine Authors: Porteous MK, Ky B, Kirkpatrick JN, Shinohara R, Diamond JM, Shah RJ, Lee JC, Christie JD, Kawut SM Tags: Am J Respir Crit Care Med Source Type: research

Increased Dead Space Ventilation Mediates Reduced Exercise Capacity in Systolic Heart Failure.
CONCLUSIONS: Low resting pulmonary diffusing capacity in heart failure is indicative of high dead-space ventilation during exercise, leading to excessive and inefficient ventilation. These findings would support the concept of pulmonary vasculopathy leading to altered ventilation perfusion matching (increased dead space) and resultant dyspnoea, independent of markers of cardiac function. PMID: 26735905 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 6, 2016 Category: Respiratory Medicine Authors: Kee K, Stuart-Andrews C, Ellis MJ, Wrobel JP, Nilsen K, Sharma M, Thompson BR, Naughton MT Tags: Am J Respir Crit Care Med Source Type: research

Alveolar-like Stem Cell-derived Myb(neg) Macrophages Promote Recovery and Survival in Airway Disease.
CONCLUSIONS: PSCs are a reliable source to produce therapeutically active alveolar-like macrophages to treat airway disease. PMID: 26730942 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 5, 2016 Category: Respiratory Medicine Authors: Litvack ML, Wigle TJ, Lee J, Wang J, Ackerley C, Grunebaum E, Post M Tags: Am J Respir Crit Care Med Source Type: research

Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.
CONCLUSIONS: Recipient plasma concentration of epithelial cell death markers (M30, M65) after lung transplantation is negatively correlated with early graft performance and long-term survival. PMID: 26796350 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 21, 2016 Category: Respiratory Medicine Authors: Hashimoto K, Besla R, Zamel R, Juvet S, Kim H, Azad S, Waddell TK, Cypel M, Liu M, Keshavjee S Tags: Am J Respir Crit Care Med Source Type: research

Center Volume and Extracorporeal Membrane Oxygenation Support at Lung Transplantation in the Lung Allocation Score Era.
CONCLUSIONS: An adverse effect of ECMO at the time of lung transplantation was evident in low-volume centers, but absent in centers with experience of performing >170 lung transplants in the first 5 years of the lung allocation score era. PMID: 26840155 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - February 3, 2016 Category: Respiratory Medicine Authors: Hayes D, Tobias JD, Tumin D Tags: Am J Respir Crit Care Med Source Type: research

Gut Microbiota Predict Pulmonary Infiltrates After Allogeneic Hematopoietic Cell Transplantation.
CONCLUSIONS: This is the first study to demonstrate prospective changes in gut microbiota associated with PCs after HCT. Post-engraftment PCs and Gammaproteobacteria-domination were predictive of mortality. This suggests an adverse relationship between graft and lung, perhaps mediated by bacterial composition in the gut. Further study is warranted. PMID: 26886180 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - February 17, 2016 Category: Respiratory Medicine Authors: Harris B, Morjaria SM, Littmann ER, Geyer AI, Stover DE, Barker JN, Giralt SA, Taur Y, Pamer EG Tags: Am J Respir Crit Care Med Source Type: research

De novo DQ-donor-specific Antibodies are Associated with Chronic Lung Allograft Dysfunction After Lung Transplantation.
CONCLUSIONS: dnDSA are common after lung transplantation, with the majority being DQ DSA. DQ dnDSA are associated with an increased risk of CLAD. Strategies to prevent or treat DQ dnDSA may improve outcomes for lung transplant recipients. PMID: 26967790 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - March 11, 2016 Category: Respiratory Medicine Authors: Tikkanen JM, Singer LG, Kim SJ, Li Y, Binnie M, Chaparro C, Chow CW, Martinu T, Azad S, Keshavjee S, Tinckam K Tags: Am J Respir Crit Care Med Source Type: research

Access to Lung Transplantation. The Long and Short of It.
PMID: 26977969 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - March 15, 2016 Category: Respiratory Medicine Authors: Weill D Tags: Am J Respir Crit Care Med Source Type: research

Recipient Selection for Lung Transplantation.
Authors: PMID: 27128711 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - April 30, 2016 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research

Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus During Macrophage Cell Death.
CONCLUSIONS: These observations identify programmed necrosis-dependent lateral transfer of Aspergillus fumigatus between macrophages as an important host strategy for controlling fungal germination. This process is critically dependent on calcineurin. Our studies provide fundamental insights into the pathogenesis of pulmonary aspergillosis in the immunocompromised host. PMID: 27163634 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 9, 2016 Category: Respiratory Medicine Authors: Shah A, Kannambath S, Herbst S, Rogers A, Soresi S, Carby M, Reed A, Mostowy S, Fisher MC, Shaunak S, Armstrong-James DP Tags: Am J Respir Crit Care Med Source Type: research

Bronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant.
Authors: PMID: 27248598 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - May 31, 2016 Category: Respiratory Medicine Tags: Am J Respir Crit Care Med Source Type: research