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Total 7677 results found since Jan 2013.
A Systematic Review of Potential Immunotherapies Targeting PRAME in Retinoid Resistant Oral Potentially Malignant Disorders and Oral Cancer
Conclusion: Our analysis of the literature suggests that PRAME screening in OC and OPMDs prior to RBT should be done. In PRAME positive cases, approaches like PRAME based immunotherapy in the form of Cancer vaccine therapy [Acellular PRAME vaccine, PRAME pulsed Dendritic Cells (DC)]; Adoptive T Cell therapy/T Cell Receptor-T Cell therapy, Antibody therapy/Chimeric Antigen Receptor-T Cell therapy along with Presented antigen modulation Therapies employing histone deacetylase inhibitors and demethylation agents seem plausible. In the future, a combination therapy employing either PRAME vaccines or antibodies or Adoptive T ce...
Source: Current Molecular Medicine - October 29, 2021 Category: Molecular Biology Authors: Ruby Dwivedi Divya Mehrotra Shaleen Chandra Rahul Pandey Source Type: research
Immunotherapy (excluding checkpoint inhibitors) for stage I to III non-small cell lung cancer treated with surgery or radiotherapy with curative intent
CONCLUSIONS: Based on this updated review, the current literature does not provide evidence that suggests a survival benefit from adding immunotherapy (excluding checkpoint inhibitors) to conventional curative surgery or radiotherapy, for people with localised NSCLC (stages I to III). Several ongoing trials with immune checkpoints inhibitors (PD-1/PD-L1) might bring new insights into the role of immunotherapy for people with stages I to III NSCLC.PMID:34870327 | DOI:10.1002/14651858.CD011300.pub3
Source: Cancer Control - December 6, 2021 Category: Cancer & Oncology Authors: Jianwei Zhu Yun Yuan Xiaoyu Wan Dan Yin Rui Li Wenwen Chen Chen Suo Huan Song Source Type: research
Concordance of Anyplex ™ II HPV HR assays with reference HPV assays in cervical cancer screening: systematic review
CONCLUSION: Five validation studies of Anyplex™ Ⅱ HPV HR performance in cervical cancer screening settings showed its consistently high absolute clinical sensitivity for both CIN2+ and CIN3+, still comparative clinical sensitivity and specificity relative to HC2 and GP5+/6 + PCR. Anyplex™ Ⅱ has evaluated HPV HR in several settings and population groups. It is considered clinically validated for primary cervical cancer screening and triage in referral population settings.PMID:34919974 | DOI:10.1016/j.jviromet.2021.114435
Source: Journal of Virological Methods - December 17, 2021 Category: Virology Authors: Habtamu Biazin Source Type: research
A systematic review and meta-analysis of immune response against first and second doses of SARS-CoV-2 vaccines in adult patients with hematological malignancies
CONCLUSION: Our findings highlight the substantially low rate of seroprotection in patients with hematological malignancies with a wide range of rates among disease subgroups and different treatments; further highlighting the fact that booster doses might be acquired for these patients to improve immunity against SARS-CoV-2.PMID:35843148 | DOI:10.1016/j.intimp.2022.109046
Source: International Immunopharmacology - July 17, 2022 Category: Allergy & Immunology Authors: Maryam Noori Shadi Azizi Farhan Abbasi Varaki Seyed Aria Nejadghaderi Davood Bashash Source Type: research
New Onset and Exacerbations of Psoriasis Following COVID-19 Vaccines: A Systematic Review
CONCLUSIONS: Both new-onset psoriasis and psoriasis flares were reported as cutaneous adverse events following COVID-19 vaccination. Psoriatic patients may require regular follow-up before and after COVID-19 vaccination.TRIAL REGISTRATION: Review registration number PROSPERO database: CRD42022304157.PMID:36048409 | DOI:10.1007/s40257-022-00721-z
Source: Cancer Control - September 1, 2022 Category: Cancer & Oncology Authors: Po-Chien Wu I-Hsin Huang Chuang-Wei Wang Cheng-Chang Tsai Wen-Hung Chung Chun-Bing Chen Source Type: research
Weekly Overseas Health IT Links – 15th October, 2022.
This article uses the one that divides providers into groups depending on the life cycle stage the clinic is at the given moment. According to this classification, medical providers fall into three groups:BeginnersGrowing clinicsWell-established providersHealth care providers are business entities, so their life cycle, like that of any business, consists of the early stage or launch, growth and maturity. At each stage, providers have different priorities and goals, and the choice of medical software solutions should be made accordingly.Medical software for beginnersThe launch phase can be tough. At this stage, the profits ...
Source: Australian Health Information Technology - October 15, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Locating sex- and gender-specific data in health promotion research: evaluating the sensitivity and precision of published filters.
CONCLUSIONS: Although search filters can facilitate the identification of research evidence to enable decision making, variability in study abstracting and indexing can limit the generalizability and usability of these filters. This potential for variability should be considered when deciding to incorporate a search filter into any literature search. This research highlights the importance of this awareness when developing strategies for searching the published literature and the potential value of supplementing database searching with other methods of study identification.
PMID: 28670208 [PubMed - in process]
Source: Journal of the Medical Library Association : JMLA - July 5, 2017 Category: Databases & Libraries Tags: J Med Libr Assoc Source Type: research
