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Vaccination: Vaccines
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The CXCR5 T follicular helper cell compartment in children with antibody deficiencies-in search of a prognostic marker of childhood hypogammaglobulinemia
CONCLUSIONS: A deficiency of Tfh cells in young infants mirrors the immaturity of the humoral immune response, whereas in older children Tfh cells are proposed as a prognostic marker facilitating to distinguish between mild hypogammaglobulinemia and the developing common variable immunodeficiency.PMID:33641302 | DOI:10.15586/aei.v49i2.34
Source: Allergologia et Immunopathologia - February 28, 2021 Category: Allergy & Immunology Authors: Aleksandra Szczawinska-Poplonyk Katarzyna Tapolska-Jozwiak Husam Samara Maciej Boruczkowski Barbara Wieckowska Source Type: research
Rwanda: Rwanda Optimistic About Latest Breakthrough in Search for a Malaria Vaccine
[New Times] Officials at Rwanda Biomedical Centre (RBC) have said they are optimistic about the recent unprecedented developments in the search for a malaria vaccine, and hope soon there will be a vaccine to complement the existing measures to fight the disease.
Source: AllAfrica News: Malaria - April 26, 2021 Category: Infectious Diseases Source Type: news
The CXCR5 T follicular helper cell compartment in children with antibody deficiencies-in search of a prognostic marker of childhood hypogammaglobulinemia
CONCLUSIONS: A deficiency of Tfh cells in young infants mirrors the immaturity of the humoral immune response, whereas in older children Tfh cells are proposed as a prognostic marker facilitating to distinguish between mild hypogammaglobulinemia and the developing common variable immunodeficiency.PMID:33641302 | DOI:10.15586/aei.v49i2.34
Source: Allergologia et Immunopathologia - February 28, 2021 Category: Allergy & Immunology Authors: Aleksandra Szczawinska-Poplonyk Katarzyna Tapolska-Jozwiak Husam Samara Maciej Boruczkowski Barbara Wieckowska Source Type: research
Plague vaccines: new developments in an ongoing search
Appl Microbiol Biotechnol. 2021 Jun 18. doi: 10.1007/s00253-021-11389-6. Online ahead of print.ABSTRACTAs the reality of pandemic threats challenges humanity, exemplified during the ongoing SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of disease has become increasingly critical. Of paramount concern are novel and reemerging pathogens that could trigger such events, including the plague bacterium Yersinia pestis. Y. pestis is responsible for more human deaths than any other known pathogen and exists globally in endemic regions of the world, including the four corners region and North...
Source: Applied Microbiology and Biotechnology - June 18, 2021 Category: Microbiology Authors: Jason A Rosenzweig Emily K Hendrix Ashok K Chopra Source Type: research
The search for a Buruli Ulcer vaccine and the effectiveness of the Bacillus Calmette-Gu érin vaccine
Acta Trop. 2022 Jan 20;228:106323. doi: 10.1016/j.actatropica.2022.106323. Online ahead of print.ABSTRACTBuruli Ulcer is a neglected tropical disease that is caused by Mycobacterium ulcerans. It is not fatal; however, it manifests a range of devastating symptoms on the hosts' bodies. Various drugs and treatments are available for the disease; however, they are often costly and have adverse effects. There is still much uncertainty regarding the mode of transmission, vectors, and reservoir. At present, there are no official vector control methods, prevention methods, or a vaccine licensed to prevent infection. The Bacillus C...
Source: Acta Tropica - January 22, 2022 Category: Infectious Diseases Authors: Tamara Z Ishwarlall Moses Okpeku Adebayo A Adeniyi Matthew A Adeleke Source Type: research
From fundamental biology to the search for innovation: The story of fungal extracellular vesicles
Eur J Cell Biol. 2022 Feb 9;101(2):151205. doi: 10.1016/j.ejcb.2022.151205. Online ahead of print.ABSTRACTFungal extracellular vesicles (EVs) have attracted increased attention in recent years. Originated from a serendipitous discovery, the initial observation of fungal EVs resulted in a set of data repetitively rejected by several scientific journals, which raised questions about their authenticity. However, after the most fundamental experimental issues related to their observation were addressed, fungal EVs were characterized in dozens of species and became an emerging field. In this essay, we will discuss these fundame...
Source: European Journal of Cell Biology - February 17, 2022 Category: Cytology Authors: Marcio L Rodrigues Leonardo Nimrichter Source Type: research
New Research Provides Hope In The Search For A Respiratory Syncytial Virus Vaccine- Part II
Respiratory syncytial virus is one of the leading causes of death for infants globally, and a safe vaccine has yet to be approved for use. However, the long search may soon be over, as new structure-based vaccine technology holds great promise.
Source: Forbes.com Healthcare News - May 3, 2022 Category: Pharmaceuticals Authors: William A. Haseltine, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & Source Type: news
