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Investigating the correlation between COVID-19 and the progression of chronic liver disease
Expert Rev Gastroenterol Hepatol. 2023 Apr 24:1-11. doi: 10.1080/17474124.2023.2206564. Online ahead of print.ABSTRACTINTRODUCTION: The novel coronavirus disease 2019 has thrown light on various heterogeneous afflictions of newly emerging viruses on the human body. Early reports demonstrated direct effect of novel coronavirus on the liver, but subsequently, this did not stand up to validation. The SARS-CoV-2 virus affects the liver differentially; in healthy compared to those with preexisting liver disease.AREAS COVERED: This exhaustive paper reviews the current, literature on mechanisms by which COVID-19 affects the healt...
Source: Expert Review of Gastroenterology and Hepatology - April 24, 2023 Category: Gastroenterology Authors: Cyriac Abby Philips Deepak Madhu Philip Augustine Source Type: research

Novel therapeutic approaches based on the pathological role of gut dysbiosis on the link between nonalcoholic fatty liver disease and insulin resistance
Eur Rev Med Pharmacol Sci. 2023 Mar;27(5):1921-1944. doi: 10.26355/eurrev_202303_31558.ABSTRACTThe growing global epidemic of obesity and type 2 diabetes mellitus has determined an increased prevalence of NAFLD (non-alcoholic fatty liver disease), making it the most common chronic liver disease in the Western world and a leading cause of liver transplantation. In the last few years, a rising number of studies conducted both on animal and human models have shown the existence of a close association between insulin resistance (IR), dysbiosis, and steatosis. However, all the mechanisms that lead to impaired permeability, infl...
Source: European Review for Medical and Pharmacological Sciences - March 17, 2023 Category: Drugs & Pharmacology Authors: E Bellucci F Chiereghin F Pacifici G Donadel A De Stefano G Malatesta M G Valente F Guadagni M Infante V Rovella A Noce M Tesauro N Di Daniele D Della Morte D Pastore Source Type: research

Acute Liver Failure: Current Updates and Management
Korean J Gastroenterol. 2023 Jan 25;81(1):17-28. doi: 10.4166/kjg.2022.148.ABSTRACTAcute liver failure (ALF) is a rare disease condition with a dynamic clinical course and catastrophic outcomes. Several etiologies are involved in ALF. Hepatitis A and B infections and indiscriminate use of untested herbs or supplemental agents are the most common causes of ALF in Korea. Noninvasive neurological monitoring tools have been used in patients with ALF in recent times. Ongoing improvements in intensive care, including continuous renal replacement therapy, therapeutic plasma exchange, vasopressor, and extracorporeal membrane oxyge...
Source: Korean J Gastroenter... - January 25, 2023 Category: Gastroenterology Authors: Jin Dong Kim Source Type: research

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