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Which Premature Infants Need Eye Exams?
Discussion Retinopathy of prematurity (ROP) is a developmental problem. Term infants have full vascularization of the retina and therefore cannot have ROP. Premature infants however do not have full vascularization (which proceeds from the periphery to the central retinal area) and therefore may have abnormal and excessive vascularization. It affects premature infants primarily < 31 weeks gestation. Although the mechanism of ROP is not completely understood, increased oxygen levels are a risk factor. Additionally there is data which shows growth factors such as vascular endothelial growth factor (VEGF) are increase,d re...
Source: PediatricEducation.org - May 31, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Top Digital Health Stories of 2018: From Amazon And Google To Gene-Edited Babies
Instead of mind-boggling inventions, 2018 was the year when national governments, as well as healthcare regulators, started to embrace digital health technologies at scale. The year when Google, Amazon, Apple or Microsoft competed head-to-head for the biggest chunks on the healthcare market, and when the buzzword of the year award went to the blockchain. Here’s our guide to the top digital health stories from last year. 2018: Under the spell of cosmos and microcosmos Every year, The Medical Futurist team sits down and collects the top stories of the past 12 months in healthcare. We put the novelties under the microscope,...
Source: The Medical Futurist - December 11, 2018 Category: Information Technology Authors: nora Tags: Business Future of Medicine Medical Professionals Patients Policy Makers Researchers Top Lists 2018 AI artificial intelligence artificial pancreas blockchain chatbot CRISPR deep learning diabetes digital health digital he Source Type: blogs

What Are Risk Factors for Bronchopulmonary Dysplasia?
Discussion Bronchopulmonary dysplasia (BPD) was first described in 1967 by Northway et.al. At that time it was described as “relatively mature preterm infants with severe respiratory failure to survive their initial respiratory distress syndrome after receiving aggressive respiratory support with high oxygen and positive pressure ventilation. Their clinical course was characterized by severe chronic respiratory failure with a radiographic picture showing areas of hyperinflation alternating with adjacent increased densities.” This is often referred to as “Old BPD.” Over time more has been learned and...
Source: PediatricEducation.org - May 10, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Integrated analysis of multiomic data reveals the role of the antioxidant network in the quality of sea buckthorn berry Research
Berries of sea buckthorn, known as the "king of vitamin C," are abundant in antioxidants, have attractive colors, and are an excellent material with which to study the relationships between berry color, antioxidants, and berry quality. No study has yet determined the molecular basis of the relationship between sea buckhorn berries and their color and antioxidant levels. By using RNA-seq, LC–MS/MS, and LC/GC-MS technology and selecting red (darkest colored) and yellow (lightest colored) sea buckthorn berries at different development stages, this study showed that the red and yellow berry resulted from a higher ratio o...
Source: FASEB Journal - May 1, 2017 Category: Biology Authors: He, C., Zhang, G., Zhang, J., Zeng, Y., Liu, J. Tags: Research Source Type: research

Spectral Diversification and Trans-Species Allelic Polymorphism during the Land-to-Sea Transition in Snakes.
Abstract Snakes are descended from highly visual lizards [1] but have limited (probably dichromatic) color vision attributed to a dim-light lifestyle of early snakes [2-4]. The living species of front-fanged elapids, however, are ecologically very diverse, with ∼300 terrestrial species (cobras, taipans, etc.) and ∼60 fully marine sea snakes, plus eight independently marine, amphibious sea kraits [1]. Here, we investigate the evolution of spectral sensitivity in elapids by analyzing their opsin genes (which are responsible for sensitivity to UV and visible light), retinal photoreceptors, and ocular lenses. We f...
Source: Current Biology - May 18, 2020 Category: Biology Authors: Simões BF, Gower DJ, Rasmussen AR, Sarker MAR, Fry GC, Casewell NR, Harrison RA, Hart NS, Partridge JC, Hunt DM, Chang BS, Pisani D, Sanders KL Tags: Curr Biol Source Type: research

Pediatric Vitreoretinal Surgery and Integrated Intraoperative Optical Coherence Tomography
Dev Ophthalmol. 2021 Mar 1;61:1-11. doi: 10.1159/000511818. Online ahead of print.ABSTRACTIntraoperative portable handheld and microscope-integrated OCT enhance the pediatric vitreoretinal surgeon's diagnostic abilities during examination under anesthesia and surgery, particularly in children who are challenging to examine preoperatively due to young age or ocular trauma. Improved OCT-guided visualization of vitreoretinal anatomic relationships has the potential to improve surgical safety and efficiency. In retinopathy of prematurity and other pediatric retinal vascular conditions, intraoperative OCT can be critical for di...
Source: Developments in Ophthalmology - March 1, 2021 Category: Opthalmology Authors: Sophie Cai Anthony Therattil Lejla Vajzovic Source Type: research