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Postbiotic as Novel Alternative Agent or Adjuvant for the Common Antibiotic Utilized in the Food Industry
CONCLUSION: Postbiotic constituents may be a new approach for utilization in the pharmaceutical and food sectors for developing therapeutic treatments. Further metabolomics investigations are required to describe novel postbiotics and clinical trials are also required to define the sufficient dose and optimum administration frequency of postbiotics.PMID:37702234 | DOI:10.2174/1389201025666230912123849
Source: Current Pharmaceutical Biotechnology - September 13, 2023 Category: Biotechnology Authors: Sama Sepordeh Amir Mohammad Jafari Sara Bazzaz Amin Abbasi Ramin Aslani Sousan Houshmandi Aziz Homayouni Rad Source Type: research

Prophylactic immunization to Helicobacter pylori infection using spore vectored vaccines
CONCLUSIONS: This study demonstrates the utility of bacterial spores for mucosal vaccination to H. pylori infection. The heat stability and robustness of Bacillus spores coupled with their existing use as probiotics make them an attractive solution for either protection against H. pylori infection or potentially for therapy and control of active infection.PMID:37314018 | DOI:10.1111/hel.12997
Source: Cancer Control - June 14, 2023 Category: Cancer & Oncology Authors: Paidamoyo M Katsande Van Duy Nguyen Thi Lan Phuong Nguyen Thi Kim Cuc Nguyen Gabrielle Mills David M D Bailey Graham Christie Huynh Anh Hong Simon M Cutting Source Type: research

Role of alternatives to antibiotics in mitigating the antimicrobial resistance crisis
Indian J Med Res. 2022 Sep;156(3):464-477. doi: 10.4103/ijmr.IJMR_3514_20.ABSTRACTAntimicrobial resistance (AMR) is a burgeoning challenge of global priority, warranting immediate action to prevent the explosion of multidrug-resistant (MDR) pathogens. Indiscriminate antimicrobial use is the most important driver for AMR. AMR has led to depletion of the antibiotic pipeline and developing new antibiotics is extremely challenging due to technical and financial issues and also resistance emerges as soon any new antibiotic is introduced. At present, preserving the power of existing antibiotics by prudent use and curtailing spre...
Source: Indian J Med Res - February 8, 2023 Category: Research Authors: Renu Gupta Sangeeta Sharma Source Type: research

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