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Specialty: Cancer & Oncology
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Total 316 results found since Jan 2013.

Social Determinants of Cancer Disparities
Ann Surg Oncol. 2023 Sep 18. doi: 10.1245/s10434-023-14200-0. Online ahead of print.ABSTRACTCancer is a major public health issue that is associated with significant morbidity and mortality across the globe. At its root, cancer represents a genetic aberration, but socioeconomic, environmental, and geographic factors contribute to different cancer outcomes for selected population subsets. The disparities in the delivery of healthcare affect all aspects of cancer management from early prevention to end-of-life care. In an effort to address the inequality in the delivery of healthcare among socioeconomically disadvantaged pop...
Source: Ann Oncol - September 18, 2023 Category: Cancer & Oncology Authors: Georgia Syrnioti Claire M Eden Josh A Johnson Chase Alston Antonia Syrnioti Lisa A Newman Source Type: research

Blueprint to hepatitis B elimination in China: A modelling analysis of clinical strategies
CONCLUSIONS: Eliminating HBV will require interventional strategies to improve diagnostic, linkage-to-care, and treatment coverages. Developing novel therapies will be crucial in further reducing HBV-related mortality and removing HBV as a public health threat.IMPACT AND IMPLICATIONS: This study explores the key developments and optimal intervention strategies needed to achieve WHO hepatitis B elimination targets by 2030 in China. It highlights that China can realise the HBV elimination targets in the incidence by 2025, and by upscaling diagnostic, linkage-to-care, and treatment coverages, up to 2 million lives could poten...
Source: Cancer Control - September 7, 2023 Category: Cancer & Oncology Authors: Rui Li Mingwang Shen Jason J Ong Fuqiang Cui Wenyi Hu Polin Chan Zhuoru Zou Shu Su Hangting Liu Lei Zhang Wai-Kay Seto William C W Wong Source Type: research

Essential cancer medicines: adding feasibility to the magnitude of clinical benefit value chain
CONCLUSION: Due to the rising costs associated with newly available therapies, structured, reproducible, and field-tested tools to evaluate the added clinical benefit from these therapies need to be implemented in pre-selecting potential candidate medicines to be included in the WHO EML. ESMO is proud to collaborate closely with WHO on this important global public health initiative.PMID:37672862 | DOI:10.1016/j.esmoop.2023.101617
Source: Cancer Control - September 6, 2023 Category: Cancer & Oncology Authors: F Roitberg T Amaral N I Cherny R Giuliani N J Latino M Galotti G Bricalli G Curigliano G Pentheroudakis D Trapani Source Type: research

A novel chitosan-based doxepin nano-formulation for chemotherapy-induced oral mucositis: a randomized, double-blinded, placebo-controlled clinical trial
CONCLUSION: Chitosan-based doxepin nano-formulation might be a promising alternative for routine treatments of oral mucositis.PMID:37668810 | DOI:10.1007/s10787-023-01325-7
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Nazafarin Samiraninezhad Mostafa Rezaee Ahmad Gholami Ali Amanati Maryam Mardani Source Type: research

Clinical implications of histologic subtypes on survival outcomes in primary mucinous ovarian carcinoma
CONCLUSIONS: The IS of PMOC had poorer survival outcomes and a higher proportion of advanced-stage tumors. Although its independent prognostic significance remains uncertain, adjuvant chemotherapy should be considered for patients with fertility preservation in the IS group.PMID:37660413 | DOI:10.1016/j.ygyno.2023.08.013
Source: Gynecologic Oncology - September 3, 2023 Category: Cancer & Oncology Authors: Hyunji Lim Yiyoung Ju Se Ik Kim Jeong Hwan Park Hee Seung Kim Hyun Hoon Chung Jae-Weon Kim Noh Hyun Park Yong-Sang Song Cheol Lee Maria Lee Source Type: research

Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
Curr Cancer Drug Targets. 2023;23(11):879-888. doi: 10.2174/1568009623666230503094346.ABSTRACTOne of the most important health problems in the world today is cancer. The World Health Organization (WHO) reported that it results in 8.9 million deaths annually. Malignant tumours and unregulated cell proliferation are features of malignant neoplasms, which can also invade nearby body regions. Hepatocellular carcinoma is the third most prevalent cause of cancer-related death worldwide and the fifth most common kind of cancer, according to a recent analysis. Patients with liver disease as well as chronic hepatitis B and C are mo...
Source: Current Cancer Drug Targets - September 1, 2023 Category: Cancer & Oncology Authors: Amrita Singh Sudhanshu Mishra Saurabh Sharma Smriti Ojha Sunil Yagnik Sudhi Pandey Source Type: research

Comparison of home-based palliative care delivered by community health workers versus usual care: research protocol for a pilot randomized controlled trial
DISCUSSION: Pal-Care is a RCT funded by the NCI to explore utilization of CHWs to deliver a home-based palliative care intervention built upon the WHO Palliative Care toolkit (PCT), as compared to a usual care control group. The long-term goal of this research is to develop an effective and sustainable model for delivering home-based palliative care for cancer patients in underserved areas.TRIAL REGISTRATION (TRN): ClinicalTrials.gov ID# NCT04972630.PMID:37658397 | DOI:10.1186/s12904-023-01235-z
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Suparna Qanungo Kathleen B Cartmell Martina Mueller Melissa Butcher Saswati Sarkar Tyler-Gail Carlson Mohan Madisetti Gaurav Kumar Source Type: research

Determinants of Cervical Cancer Screening Among Women Aged 30-49 Years Old in Four African Countries: A Cross-Sectional Secondary Data Analysis
CONCLUSION: The prevalence of cervical cancer screening in Kenya, Cameroon, Nambia, and Zimbabwe was low as compared to World Health Organization (WHO) recommendations. Age, residence, work status, smoking status, women's age at first birth, condom use, husbands having work, wealth status, and health insurance were the identified determinants of cervical cancer screening. Programme and policy interventions could address younger, rural residence women, poor wealth status women, women without work, and those who never use health insurance for the uptake of cervical cancer screening.PMID:37656980 | DOI:10.1177/10732748231195681
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Melsew Setegn Alie Yilkal Negesse Mengistu Ayenew Source Type: research

Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
Curr Cancer Drug Targets. 2023;23(11):879-888. doi: 10.2174/1568009623666230503094346.ABSTRACTOne of the most important health problems in the world today is cancer. The World Health Organization (WHO) reported that it results in 8.9 million deaths annually. Malignant tumours and unregulated cell proliferation are features of malignant neoplasms, which can also invade nearby body regions. Hepatocellular carcinoma is the third most prevalent cause of cancer-related death worldwide and the fifth most common kind of cancer, according to a recent analysis. Patients with liver disease as well as chronic hepatitis B and C are mo...
Source: Current Cancer Drug Targets - September 1, 2023 Category: Cancer & Oncology Authors: Amrita Singh Sudhanshu Mishra Saurabh Sharma Smriti Ojha Sunil Yagnik Sudhi Pandey Source Type: research