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Drug landscape in patients receiving general outpatient palliative care in Germany: results from a retrospective analysis of 10,464 patients
CONCLUSIONS: Our results support the role of GOPC as an important element in improving pharmacological symptom control and deprescription to improve quality of life of patients at the end of their life.PMID:37596590 | DOI:10.1186/s12904-023-01231-3
Source: Cancer Control - August 18, 2023 Category: Cancer & Oncology Authors: Sven H Loosen Jacqueline Schwartz Steven Grewe Sarah Krieg Andreas Krieg Tom Luedde Yann-Nicolas Batzler Karel Kostev Martin Neukirchen Christoph Roderburg Source Type: research

Determinants of lipid-lowering medication prescribing in a multi-ethnic adult population diagnosed with familial hypercholesterolaemia in South London
CONCLUSION: The study suggests important determinants of lipid-lowering prescribing in an ethnically diverse adult population included older age, male sex, hypertension, and diabetes. Ethnicity showed no significant associations with lipid-lowering prescribing after adjusting for other determinants including deprivation measures.PMID:37479297 | DOI:10.3399/bjgp23X734145
Source: The British Journal of General Practice - July 21, 2023 Category: Primary Care Authors: Aya Ayoub Ralph Akyea Veline L'Esperance Salma Ayis Divya Parmar Stevo Durbaba Mark Fisher Riyaz Patel Seeromanie Harding Anthony S Wierzbicki Nadeem Qureshi Mariam Molokhia Source Type: research

Associations between education level, blood-lipid measurements and statin treatment in a Danish primary health care population from 2000 to 2018
CONCLUSION: Higher education was associated with earlier statin prescription, although the higher educated group was monitored less frequently. There was no difference in reaching treatment goal between the three education groups. These findings suggest patients with higher education level achieve an earlier dyslipidemia prevention intervention with an equally satisfying result compared to lower education patients.Key PointsLittle is known about the role of social inequality as a possible barrier for managing hypercholesterolemia in general practice.Increasing education level was associated to less frequent measurement and...
Source: Primary Care - April 10, 2023 Category: Primary Care Authors: Marius M ølsted Flege Margit Kriegbaum Henrik J ørgensen Bent Lind Lise Bathum Christen Andersen Anna Engell Source Type: research

Cancer history as a predictor in cardiovascular risk scores: a primary care cohort study
CONCLUSION: Developers should consider including cancer history variables in future cardiovascular risk models.PMID:36443065 | DOI:10.3399/BJGP.2022.0088
Source: The British Journal of General Practice - November 28, 2022 Category: Primary Care Authors: Helen Strongman Emily Herrett Rod Jackson Michael Sweeting Alexander R Lyon Susannah Stanway Claire Lawson Umesh Kadam Liam Smeeth Krishnan Bhaskaran Source Type: research

Pharmacological Treatment of Diabetic and Non-Diabetic Patients With Coronary Artery Disease in the Real World of General Practice
Front Pharmacol. 2022 Mar 24;13:858385. doi: 10.3389/fphar.2022.858385. eCollection 2022.ABSTRACTType 2 diabetes mellitus (T2DM) severely increases the probability of developing coronary artery disease (CAD), and diabetic patients with CAD should be considered at very high cardiovascular risk. The complexity of this clinical scenario makes very hard the appropriateness of the pharmacological treatment in the real world. To investigate the implementation of guideline recommendations for the treatment of patients affected by CAD with or without T2DM, a retrospective observational study was carried out between 2018 and 2020, ...
Source: Atherosclerosis - April 11, 2022 Category: Cardiology Authors: Michelangelo Rottura Antonino Molonia Domenico Antonio Giorgi Sebastiano Marino Riccardo Scoglio Giovanni Pallio Natasha Irrera Egidio Imbalzano Domenica Altavilla Giovanni Squadrito Francesco Squadrito Vincenzo Arcoraci Source Type: research

Tolerability of statin-based management of patients with a history of statin-associated muscle symptoms: protocol for a systematic review
Introduction Statin-associated muscle symptoms (SAMSs) are a major clinical issue in the primary and secondary prevention of cardiovascular events. Current guidelines advise various approaches mainly based on expert opinion. We will lead a systematic review and meta-analysis to explore the tolerability and acceptability and effectiveness of statin-based therapy management of patients with a history of SAMS. We aim to provide evidence on the tolerability and different strategies of statin-based management of patients with a history of SAMS. Methods and analysis We will conduct a systematic review of randomised controlled t...
Source: BMJ Open - August 3, 2021 Category: General Medicine Authors: Villoz, F., Lyko, C., Del Giovane, C., Rodondi, N., Blum, M. R. Tags: Open access, General practice / Family practice Source Type: research

Feasibility of improving identification of familial hypercholesterolaemia in general practice: intervention development study
Conclusions The intervention is feasible to implement in GP, and facilitates recruitment of patients with raised cholesterol for targeted assessment and identification of FH. Extracting data directly from electronic records could be used to evaluate relevant outcome measures in a future trial.
Source: BMJ Open - May 25, 2016 Category: Journals (General) Authors: Qureshi, N., Weng, S., Tranter, J., El-Kadiki, A., Kai, J. Tags: Open access, Cardiovascular medicine, General practice / Family practice, Health services research Source Type: research

Changes in metabolic parameters in patients with severe mental illness over a 10-year period: A retrospective cohort study.
CONCLUSION: Increasing body mass index relates to increasing rates of dysglycaemia over time. Measures to encourage weight reduction should be key strategies to reduce dysglycaemia rates in severe mental illness. Prescribing statins may have been effective in improving the lipid profile in this group. PMID: 26769981 [PubMed - as supplied by publisher]
Source: The Australian and New Zealand Journal of Psychiatry - January 14, 2016 Category: Psychiatry Authors: Heald AH, Martin JL, Payton T, Khalid L, Anderson SG, Narayanan RP, De Hert M, Yung A, Livingston M Tags: Aust N Z J Psychiatry Source Type: research