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Specialty: Drugs & Pharmacology
Management: General Practices
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Total 45 results found since Jan 2013.
Prescriptive behavior of non-vitamin K oral anticoagulants in patients affected by atrial fibrillation in general practice
Biomed Pharmacother. 2023 Jun 21;165:115020. doi: 10.1016/j.biopha.2023.115020. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and in recent years the pharmacological approach has been strongly implemented; in Italy, the prescription of the non-vitamin K oral anticoagulants (NOAC) was also extended to General Practitioners (GPs) since 2020. The aim of the present study was to investigate the GPs prescribing behaviour of NOACs. An observational study was performed by using the computerized medical record of 14 GPs in Sicily: patients affected by AF were selected and st...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 23, 2023 Category: Drugs & Pharmacology Authors: M Rottura S F A Drago A Molonia N Irrera S Marino R Scoglio L Orlando M Gigliotti De Fazio F Squadrito V Arcoraci E Imbalzano on the behalf of Audit & Research Messina Primary Care Group Source Type: research
Decongestants, proton pump inhibitors, and systemic antibiotics are  associated with an increased occurrence of dysbiosis
CONCLUSION: The study provides evidence that treatment with decongestants and other nasal preparations is strongly associated with an increased occurrence of dysbiosis. Although the pathophysiology of dysbiosis is multifactorial and confounding factors cannot be ruled out, the close correlation seen may have clinical significance.PMID:36594656 | DOI:10.5414/CP204294
Source: Clinical Pharmacology and Therapeutics - January 3, 2023 Category: Drugs & Pharmacology Authors: Seung-Young Chung Karel Kostev Christian Tanislav Source Type: research
Clinical relevance of drug-drug interactions with antibiotics as listed in a national medication formulary: results from two large population-based case-control studies in patients aged 65-100  years using linked English primary care and hospital data
In conclusion. no evidence of substantial risk was found for multiple DDIs with antibiotics despite warnings of severe outcomes in a national formulary and flagging in EHR software. It is proposed that the evidence-base for inclusion of DDIs into national formularies is strengthened and made publicly accessible and indiscriminate flagging, which compounds alert-fatigue, be reduced.PMID:36448824 | DOI:10.1002/cpt.2807
Source: Clinical Pharmacology and Therapeutics - November 30, 2022 Category: Drugs & Pharmacology Authors: Tjeerd Pieter van Staa Munir Pirmohamed Anita Sharma Iain Buchan Darren M Ashcroft Source Type: research
Documentation of Just in Case (JiC) medication for end of life patients in care homes looked after by a general practice
CONCLUSION: This evaluation has identified documentation errors and discrepancies between practice and community records of JiC medication. A newly generated practice specific flow chart was created, with an aim of reducing the discrepancies. A guide of how to carry out a QI project like this was created for the RCGP and can be found on their website. A seminar at Bristol, North Somerset, and South Gloucestershire (BNSSG) CCG to present this project took place in 2021.PMID:35871367 | DOI:10.3233/JRS-227023
Source: International Journal of Risk and Safety in Medicine - July 24, 2022 Category: Drugs & Pharmacology Authors: Eve Barnes Caroline Parfit Source Type: research
Analysis of Information on Drug Adverse Reactions Using U.S. Food and Drug Administration Adverse Event Reporting System (FAERS)
Yakugaku Zasshi. 2022;142(4):341-344. doi: 10.1248/yakushi.21-00178-5.ABSTRACTNowadays, medical big data has been developed and made available in a variety of fields such as epidemiology and pharmacovigilance. Spontaneous reporting databases are one category of medical big data and that has been adequate for analysing events related to side effects that rarely occur in general practice. These data are freely available in several countries. In Japan, the Pharmaceuticals and Medical Devices Agency has developed the Japanese Adverse Drug Event Report (JADER), and the Food and Drug Administration (FDA) developed the FDA Advers...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 4, 2022 Category: Drugs & Pharmacology Authors: Daisuke Nango Tuyoshi Sekizuka Makoto Goto Hirotoshi Echizen Source Type: research
