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Therapy: Radiation Therapy

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Total 1272 results found since Jan 2013.

Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer
CONCLUSIONS: Our results suggest that GG 1 patients already show a low level of failure at a standard dose of 77 Gy, limiting the additional benefit of focal boosting. In contrast, patients with high-risk characteristics, especially GG 4 or 5, show a low 5-year DFS, while focal boosting might improve this substantially. This suggests that reaching a high focal boost dose may be particularly beneficial for these patients.PMID:37725026 | DOI:10.1016/j.ijrobp.2023.07.044
Source: Health Physics - September 19, 2023 Category: Physics Authors: Karol ína Menne Guricová Veerle Groen Floris Pos Evelyn Monninkhof Sjoerd G Elias Karin Haustermans Robert J Smeenk Jochem van der Voort van Zyp C édric Draulans Sofie Isebaert Petra J van Houdt Linda G W Kerkmeijer Uulke A van der Heide Source Type: research

The influence of patient positioning and immobilization equipment on MR image quality and image registration in radiation therapy
CONCLUSION: The image quality reduction in the RT setup was due to the imaged region's anatomy and its position relative to the applied coil. Furthermore, optimizing the pulse sequence is crucial for MR imaging in RT applications. Although the use of immobilization equipment may decrease the image quality in the RT setup, it does not affect organ delineation, and the image quality is still satisfactory for this purpose. Also, the use of immobilization equipment in the RT setup has increased registration accuracy.PMID:37716368 | DOI:10.1002/acm2.14162
Source: Journal of Applied Clinical Medical Physics - September 16, 2023 Category: Physics Authors: Atefeh Rostami Mostafa Robatjazi Seyed Alireza Javadinia Nematullah Shomoossi Ramin Shahraini Source Type: research

Analysis and prediction of liver volume change maps derived from computational tomography scans acquired pre- and post-radiation therapy
This study leverages the use of deep learning-based segmentation and biomechanical deformable image registration (DIR) to analyze and predict this relationship. Pre- and Post-EBRT imaging data were collected for 100 patients treated for HCC, CC or CRC with IMRT with prescription doses ranging from 50 to 100 Gy delivered in 10 to 28 fractions. For each patient, DIR between the portal and venous (PV) phase of a diagnostic CT scan acquired before RT planning, and a PV phase of a diagnostic CT scan acquired after the end of RT (on average 147±36 days) was performed to calculate Jacobian maps representing volume changes in the...
Source: Physics in Medicine and Biology - September 15, 2023 Category: Physics Authors: Guillaume Cazoulat Aashish C Gupta Mais M Al Taie Eugene J Koay Kristy K Brock Source Type: research

Deep learning in MRI-guided radiation therapy: A systematic review
J Appl Clin Med Phys. 2023 Sep 15:e14155. doi: 10.1002/acm2.14155. Online ahead of print.ABSTRACTRecent advances in MRI-guided radiation therapy (MRgRT) and deep learning techniques encourage fully adaptive radiation therapy (ART), real-time MRI monitoring, and the MRI-only treatment planning workflow. Given the rapid growth and emergence of new state-of-the-art methods in these fields, we systematically review 197 studies written on or before December 31, 2022, and categorize the studies into the areas of image segmentation, image synthesis, radiomics, and real time MRI. Building from the underlying deep learning methods,...
Source: Journal of Applied Clinical Medical Physics - September 15, 2023 Category: Physics Authors: Zach Eidex Yifu Ding Jing Wang Elham Abouei Richard L J Qiu Tian Liu Tonghe Wang Xiaofeng Yang Source Type: research

Analysis and prediction of liver volume change maps derived from computational tomography scans acquired pre- and post-radiation therapy
This study leverages the use of deep learning-based segmentation and biomechanical deformable image registration (DIR) to analyze and predict this relationship. Pre- and Post-EBRT imaging data were collected for 100 patients treated for HCC, CC or CRC with IMRT with prescription doses ranging from 50 to 100 Gy delivered in 10 to 28 fractions. For each patient, DIR between the portal and venous (PV) phase of a diagnostic CT scan acquired before RT planning, and a PV phase of a diagnostic CT scan acquired after the end of RT (on average 147±36 days) was performed to calculate Jacobian maps representing volume changes in the...
Source: Physics in Medicine and Biology - September 15, 2023 Category: Physics Authors: Guillaume Cazoulat Aashish C Gupta Mais M Al Taie Eugene J Koay Kristy K Brock Source Type: research

Deep learning in MRI-guided radiation therapy: A systematic review
J Appl Clin Med Phys. 2023 Sep 15:e14155. doi: 10.1002/acm2.14155. Online ahead of print.ABSTRACTRecent advances in MRI-guided radiation therapy (MRgRT) and deep learning techniques encourage fully adaptive radiation therapy (ART), real-time MRI monitoring, and the MRI-only treatment planning workflow. Given the rapid growth and emergence of new state-of-the-art methods in these fields, we systematically review 197 studies written on or before December 31, 2022, and categorize the studies into the areas of image segmentation, image synthesis, radiomics, and real time MRI. Building from the underlying deep learning methods,...
Source: Journal of Applied Clinical Medical Physics - September 15, 2023 Category: Physics Authors: Zach Eidex Yifu Ding Jing Wang Elham Abouei Richard L J Qiu Tian Liu Tonghe Wang Xiaofeng Yang Source Type: research

Robust mixed electron-photon radiation therapy planning for soft tissue sarcoma
CONCLUSION: For STS with subcutaneous involvement, MBRT offers statistically significant sparing of OARs without sacrificing target coverage when compared to VMAT. MBRT plans are deliverable on conventional linacs without the use of electron applicators, shortened source-to-surface distance (SSD) or bolus. This study shows that MBRT is a logistically feasible technique with clear dosimetric benefits.PMID:37681990 | DOI:10.1002/mp.16709
Source: Health Physics - September 8, 2023 Category: Physics Authors: Veng Jean Heng Monica Serban Marc-Andr é Renaud Carolyn Freeman Jan Seuntjens Source Type: research

Shallow kinetics induced by a metronome (SKIM): A novel contactless respiratory motion management
CONCLUSION: Compared with FB, SKIM can significantly reduce respiratory motion magnitude of thoracic targets. The difference in maximum motion reduction in the overall vector norm, S-I, and A-P directions was significant (p = 0.033, 0.042, 0.011). Our proposed method can be an excellent practical alternative to conventional compression due to its flexibility and ease of implementation.PMID:37672210 | DOI:10.1002/acm2.14147
Source: Journal of Applied Clinical Medical Physics - September 6, 2023 Category: Physics Authors: James Sohn Mitchell Polizzi Philip Reed McDonagh Christopher Guy Rabten Datsang Elisabeth Weiss Siyong Kim Source Type: research

Current status of the educational environment to acquire and maintain the professional skills of radiotherapy technology and medical physics specialists in Japan: a nationwide survey
This study aimed to investigate the educational environment of radiotherapy technology and medical physics specialists (RTMP) in Japan. We conducted a nationwide questionnaire survey in radiotherapy institutions between June and August 2022. Participants were asked questions regarding the educational system, perspectives on updating RTMP's skills and qualifications, and perspectives on higher education for RTMP at radiotherapy institutions. The results were then analyzed in detail according to three factors: whether the hospital was designed for cancer care, whether it was a Japanese Society for Radiation Oncology (JASTRO)...
Source: Health Physics - September 5, 2023 Category: Physics Authors: Naoki Hayashi Masahiko Okumura Mitsuhiro Nakamura Yoshitomo Ishihara Seiichi Ota Naoki Tohyama Kohei Shimomura Hiroyuki Okamoto Hiroshi Onishi Source Type: research

Preliminary study on dosimetry characteristics of a novel cylindrical dose verification system
CONCLUSIONS: This novel ionization chamber array demonstrates good dosimetry characteristics and is suitable for clinical IMRT and VMAT plan verifications.PMID:37665789 | DOI:10.1002/acm2.14138
Source: Journal of Applied Clinical Medical Physics - September 4, 2023 Category: Physics Authors: Long He Jinhan Zhu Xuetao Wang Bailin Zhang Qiang Hu Lixin Chen Xiaowei Liu Source Type: research