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Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance
Adv Cancer Res. 2023;160:133-203. doi: 10.1016/bs.acr.2023.03.002. Epub 2023 Apr 7.ABSTRACTLong noncoding RNAs (lncRNAs) comprise a diverse class of RNA molecules that regulate various physiological processes and have been reported to be involved in several human pathologies ranging from neurodegenerative disease to cancer. Therapeutic resistance is a major hurdle for cancer treatment. Over the past decade, several studies has emerged on the role of lncRNAs in cancer drug resistance and many trials have been conducted employing them. LncRNAs also regulate different cell death pathways thereby maintaining a fine balance of ...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Sandhik Nandi Atanu Mondal Aritra Ghosh Shravanti Mukherjee Chandrima Das Source Type: research
PFKP: More than phosphofructokinase
Adv Cancer Res. 2023;160:1-15. doi: 10.1016/bs.acr.2023.03.001. Epub 2023 Mar 30.ABSTRACTPhosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions. PFKP performs its function not only in the cytoplasm, but also at the cell membrane, on the mitochondria, at the lysosomal membrane, and in the nucleus. The functions of PFKP are extensively studied in cancer cells. PFKP is also highly expressed in certain immune cells; nevertheless, th...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Haizhen Wang Tiffany Penaloza Amanda J Manea Xueliang Gao Source Type: research
Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance
Adv Cancer Res. 2023;160:133-203. doi: 10.1016/bs.acr.2023.03.002. Epub 2023 Apr 7.ABSTRACTLong noncoding RNAs (lncRNAs) comprise a diverse class of RNA molecules that regulate various physiological processes and have been reported to be involved in several human pathologies ranging from neurodegenerative disease to cancer. Therapeutic resistance is a major hurdle for cancer treatment. Over the past decade, several studies has emerged on the role of lncRNAs in cancer drug resistance and many trials have been conducted employing them. LncRNAs also regulate different cell death pathways thereby maintaining a fine balance of ...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Sandhik Nandi Atanu Mondal Aritra Ghosh Shravanti Mukherjee Chandrima Das Source Type: research
PFKP: More than phosphofructokinase
Adv Cancer Res. 2023;160:1-15. doi: 10.1016/bs.acr.2023.03.001. Epub 2023 Mar 30.ABSTRACTPhosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions. PFKP performs its function not only in the cytoplasm, but also at the cell membrane, on the mitochondria, at the lysosomal membrane, and in the nucleus. The functions of PFKP are extensively studied in cancer cells. PFKP is also highly expressed in certain immune cells; nevertheless, th...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Haizhen Wang Tiffany Penaloza Amanda J Manea Xueliang Gao Source Type: research
Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance
Adv Cancer Res. 2023;160:133-203. doi: 10.1016/bs.acr.2023.03.002. Epub 2023 Apr 7.ABSTRACTLong noncoding RNAs (lncRNAs) comprise a diverse class of RNA molecules that regulate various physiological processes and have been reported to be involved in several human pathologies ranging from neurodegenerative disease to cancer. Therapeutic resistance is a major hurdle for cancer treatment. Over the past decade, several studies has emerged on the role of lncRNAs in cancer drug resistance and many trials have been conducted employing them. LncRNAs also regulate different cell death pathways thereby maintaining a fine balance of ...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Sandhik Nandi Atanu Mondal Aritra Ghosh Shravanti Mukherjee Chandrima Das Source Type: research
PFKP: More than phosphofructokinase
Adv Cancer Res. 2023;160:1-15. doi: 10.1016/bs.acr.2023.03.001. Epub 2023 Mar 30.ABSTRACTPhosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions. PFKP performs its function not only in the cytoplasm, but also at the cell membrane, on the mitochondria, at the lysosomal membrane, and in the nucleus. The functions of PFKP are extensively studied in cancer cells. PFKP is also highly expressed in certain immune cells; nevertheless, th...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Haizhen Wang Tiffany Penaloza Amanda J Manea Xueliang Gao Source Type: research
Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance
Adv Cancer Res. 2023;160:133-203. doi: 10.1016/bs.acr.2023.03.002. Epub 2023 Apr 7.ABSTRACTLong noncoding RNAs (lncRNAs) comprise a diverse class of RNA molecules that regulate various physiological processes and have been reported to be involved in several human pathologies ranging from neurodegenerative disease to cancer. Therapeutic resistance is a major hurdle for cancer treatment. Over the past decade, several studies has emerged on the role of lncRNAs in cancer drug resistance and many trials have been conducted employing them. LncRNAs also regulate different cell death pathways thereby maintaining a fine balance of ...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Sandhik Nandi Atanu Mondal Aritra Ghosh Shravanti Mukherjee Chandrima Das Source Type: research
PFKP: More than phosphofructokinase
Adv Cancer Res. 2023;160:1-15. doi: 10.1016/bs.acr.2023.03.001. Epub 2023 Mar 30.ABSTRACTPhosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions. PFKP performs its function not only in the cytoplasm, but also at the cell membrane, on the mitochondria, at the lysosomal membrane, and in the nucleus. The functions of PFKP are extensively studied in cancer cells. PFKP is also highly expressed in certain immune cells; nevertheless, th...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Haizhen Wang Tiffany Penaloza Amanda J Manea Xueliang Gao Source Type: research
Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance
Adv Cancer Res. 2023;160:133-203. doi: 10.1016/bs.acr.2023.03.002. Epub 2023 Apr 7.ABSTRACTLong noncoding RNAs (lncRNAs) comprise a diverse class of RNA molecules that regulate various physiological processes and have been reported to be involved in several human pathologies ranging from neurodegenerative disease to cancer. Therapeutic resistance is a major hurdle for cancer treatment. Over the past decade, several studies has emerged on the role of lncRNAs in cancer drug resistance and many trials have been conducted employing them. LncRNAs also regulate different cell death pathways thereby maintaining a fine balance of ...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Sandhik Nandi Atanu Mondal Aritra Ghosh Shravanti Mukherjee Chandrima Das Source Type: research
PFKP: More than phosphofructokinase
Adv Cancer Res. 2023;160:1-15. doi: 10.1016/bs.acr.2023.03.001. Epub 2023 Mar 30.ABSTRACTPhosphofructokinase (PFK) is one of the key enzymes that functions in glycolysis. Studies show that PFKP regulates cell proliferation, apoptosis, autophagy, cell migration/metastasis, and stemness through glycolysis and glycolysis-independent functions. PFKP performs its function not only in the cytoplasm, but also at the cell membrane, on the mitochondria, at the lysosomal membrane, and in the nucleus. The functions of PFKP are extensively studied in cancer cells. PFKP is also highly expressed in certain immune cells; nevertheless, th...
Source: Advances in Cancer Research - September 13, 2023 Category: Cancer & Oncology Authors: Haizhen Wang Tiffany Penaloza Amanda J Manea Xueliang Gao Source Type: research
Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence
J Cell Mol Med. 2023 Sep 12. doi: 10.1111/jcmm.17936. Online ahead of print.ABSTRACTThe most common type of cancer in the world is lung cancer. Traditional treatments have an important role in cancer therapy. In the present review, the most recent findings on the effects of medicinal plants and their constituents or natural products (NP) in treating lung cancer are discussed. Empirical studies until the end of March 2022 were searched using the appropriate keywords through the databases PubMed, Science Direct and Scopus. The extracts and essential oils tested were all shown to effect lung cancer by several mechanisms inclu...
Source: Molecular Medicine - September 12, 2023 Category: Molecular Biology Authors: Arghavan Memarzia Saeideh Saadat Fereshteh Asgharzadeh Sepide Behrouz Gert Folkerts Mohammad Hossein Boskabady Source Type: research
Research progress on Th22 cells and related cytokines in tumors: current status and future perspectives
This article will hopefully inspire new future directions in the research on cancer therapy.PMID:37693133 | PMC:PMC10492103
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Zhi-Ning Wang Tao Xu Kang-Sheng Liu Source Type: research
