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Nutrition: Diets

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Total 538 results found since Jan 2013.

Tumor lipid metabolism: a mechanistic link between diet and cancer progression
Curr Opin Biotechnol. 2023 Sep 13;84:102993. doi: 10.1016/j.copbio.2023.102993. Online ahead of print.ABSTRACTThe potential for 'anti-cancer' diets to markedly alter cancer risk and prognosis has captured the imagination of patients, physicians, and researchers alike, but many of these dietary recommendations come from correlative studies that attribute certain diets to altered cancer risk. While provocative, little is known about the molecular mechanisms behind how these dietary interventions impact cancer progression. Within this context, however, changes in tumor lipid metabolism are emerging as a key contributor. In th...
Source: Current Opinion in Biotechnology - September 16, 2023 Category: Biotechnology Authors: Yu-Jin Jeong Thomas J Rogers Carolyn E Anderson Evan C Lien Source Type: research

GLUT5: structure, functions, diseases and potential applications
Acta Biochim Biophys Sin (Shanghai). 2023 Sep 7. doi: 10.3724/abbs.2023158. Online ahead of print.ABSTRACTGlucose transporter 5 (GLUT5) is a membrane transporter that specifically transports fructose and plays a key role in dietary fructose uptake and metabolism. In recent years, a high fructose diet has occupied an important position in the daily intake of human beings, resulting in a significant increase in the incidence of obesity and metabolic diseases worldwide. Over the past few decades, GLUT5 has been well understood to play a significant role in the pathogenesis of human digestive diseases. Recently, the role of GL...
Source: Acta Biochimica et Biophysica Sinica - September 7, 2023 Category: Biochemistry Authors: Aqian Song Yuanpeng Mao Hongshan Wei Source Type: research

Epigenetic inhibitors and their role in cancer therapy
Int Rev Cell Mol Biol. 2023;380:211-251. doi: 10.1016/bs.ircmb.2023.04.005. Epub 2023 Aug 1.ABSTRACTEpigenetic modifications to DNA are crucial for normal cellular and biological functioning. DNA methylation, histone modifications, and chromatin remodeling are the most common epigenetic mechanisms. These changes are heritable but still reversible. The aberrant epigenetic alterations, such as DNA methylation, histone modification, and non-coding RNA (ncRNA)-mediated gene regulation, play an essential role in developing various human diseases, including cancer. Recent studies show that synthetic and dietary epigenetic inhibi...
Source: International Review of Cell and Molecular Biology - September 1, 2023 Category: Cytology Authors: Nouha Abdelaziz Lubna Therachiyil Hana Q Sadida Ateeque Mohamed Ali Omar S Khan Mayank Singh Abdul Q Khan Ammira S Al-Shabeeb Akil Ajaz A Bhat Shahab Uddin Source Type: research