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The perioperative complications and short-term death in endovascular treatment for acute stroke induced by extracranial carotid occlusion: a systematic review and a meta-analysis
CONCLUSIONS: EVT can effectively improve neurological function and reduce 90-day mortality for acute extracranial carotid occlusion patients without increasing the risk of symptomatic intracranial hemorrhage. Endovascular therapy is safe to perform from 6 to 24 hours after symptom onset.PMID:33755964 | DOI:10.26355/eurrev_202103_25259
Source: European Review for Medical and Pharmacological Sciences - March 23, 2021 Category: Drugs & Pharmacology Authors: G-M Cao J Hu H-L Dong Source Type: research

Medical prevention and treatment of radiation-induced carotid injury.
Abstract Radiotherapy has significantly improved the survival of cancer patients but is also associated with several adversities, including radiation-induced carotid injury (RICI). The RICI mechanisms are complex, including vessel inflammatory injury, carotid atherosclerosis, intimal proliferation, media necrosis, and peri-adventitial fibrosis. The main manifestation and adverse consequence of RICI is carotid artery stenosis (CAS), which can lead to stroke and transient ischemic attack. Currently, carotid artery injury is primarily diagnosed via color-coded duplex sonography. Early detection of traumatic changes i...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 25, 2020 Category: Drugs & Pharmacology Authors: Zheng Z, Zhao Q, Wei J, Wang B, Wang H, Meng L, Xin Y, Jiang X Tags: Biomed Pharmacother Source Type: research

Evaluation of Cardiovascular Disease Risk in HIV-1 –Infected Patients Treated with Darunavir
ConclusionsThis comprehensive review of Janssen-sponsored clinical trial, post-marketing, and epidemiological data does not suggest that CVD should be considered an important risk for users of darunavir.
Source: Drugs in R&D - September 1, 2018 Category: Drugs & Pharmacology Source Type: research