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In vitro study about prevention of vascular reocclusion by low intensity ultrasonic irradiation
Drug Discov Ther. 2022 Oct 9. doi: 10.5582/ddt.2022.01064. Online ahead of print.ABSTRACTFor the treatment of acute ischemic stroke, the current standard of care is thrombolysis by the administration of intravenous (IV) recombinant tissue-type plasminogen activator (rt-PA). Although this approach is proven to be effective, reocclusion within 24 hours occurs in about 20% of patients who receive recanalization by rt-PA. In addition, the administration of anticoagulants within 24 hours after IV rt-PA increases the risk of intracranial hemorrhage; therefore, treatment with anticoagulants is contraindicated in this population. ...
Source: Drug Discoveries and Therapeutics - October 10, 2022 Category: Drugs & Pharmacology Authors: Yoshikazu Sawaguchi Zuojun Wang Hiroyuki Yamamoto Norio Nakata Source Type: research

Comparison of the risk of cardiovascular diseases, stroke, and diabetes among the selected group of football referees and the group of general population men from Northern Poland - a pilot study
CONCLUSIONS: Thanks to properly planned and systematically continued physical activity, despite non-compliance with certain pro-health principles (increased sweet supply and consumption of alcoholic beverages), football referees are characterized by the correct body fat volume and low level of visceral adipose tissue. The parameters were found to be markedly higher in the control group of randomly selected men from the general population. The risk of diabetes, stroke, and cardiovascular diseases among football referees was found to be very low.PMID:35587065 | DOI:10.26355/eurrev_202205_28732
Source: Pharmacological Reviews - May 19, 2022 Category: Drugs & Pharmacology Authors: J Weso łowska A Jurczak S Wieder-Huszla K Jarosz A Jurewicz M Marchlewicz Source Type: research

Cinnamon and Aspirin for Mild Ischemic Stroke or Transient Ischemic Attack: A Pilot Trial
Clin Ther. 2022 Mar 25:S0149-2918(22)00082-0. doi: 10.1016/j.clinthera.2022.02.012. Online ahead of print.ABSTRACTPURPOSE: Cinnamon can reduce levels of blood lipids, blood glucose, and inflammation, which are risk factors for ischemic stroke and transient ischemic attack (TIA).The goal of this study was to observe the safety and efficacy of aspirin combined with cinnamon in the treatment of patients with mild stroke or TIA.METHODS: This pilot study included patients with mild stroke or TIA treated at Guangdong Provincial People's Hospital-Nanhai Hospital between January 2014 and December 2016. The primary end point was re...
Source: Clinical Therapeutics - March 29, 2022 Category: Drugs & Pharmacology Authors: Lei Zhang Zhanhui Li Yuewen Wu Yanming Fan Zhicong He Peng He Jingxing Liang Source Type: research

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